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HPPE

🥰Excellent
Catalog No. T67920Cas No. 1325721-55-8

HPPE is a selective inhibitor of Bach1 that acts non-electrophilically. HPPE targets the heme-binding sites on the Bach1 protein and leads to the alleviation of Bach1-mediated repression.

HPPE

HPPE

🥰Excellent
Purity: 99.36%
Catalog No. T67920Cas No. 1325721-55-8
HPPE is a selective inhibitor of Bach1 that acts non-electrophilically. HPPE targets the heme-binding sites on the Bach1 protein and leads to the alleviation of Bach1-mediated repression.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$48In StockIn Stock
5 mg$113In StockIn Stock
10 mg$178In StockIn Stock
25 mg$297In StockIn Stock
50 mg$453In StockIn Stock
1 mL x 10 mM (in DMSO)$127In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.36%
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COA HNMR LCMS

Product Introduction

Bioactivity
Description
HPPE is a selective inhibitor of Bach1 that acts non-electrophilically. HPPE targets the heme-binding sites on the Bach1 protein and leads to the alleviation of Bach1-mediated repression.
Chemical Properties
Molecular Weight479.48
FormulaC21H20F3N5O3S
Cas No.1325721-55-8
SmilesCN1C=2C(N=C1NC=3SC=4C(N3)=CC=C(C(F)(F)F)C4)=CC(C(NCCOCCO)=O)=CC2
Relative Density.1.52 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
Ethanol: 3.6 mg/mL (7.51 mM), Sonication is recommended.
DMSO: 55 mg/mL (114.71 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.0856 mL10.4280 mL20.8559 mL104.2796 mL
5 mM0.4171 mL2.0856 mL4.1712 mL20.8559 mL
DMSO
1mg5mg10mg50mg
10 mM0.2086 mL1.0428 mL2.0856 mL10.4280 mL
20 mM0.1043 mL0.5214 mL1.0428 mL5.2140 mL
50 mM0.0417 mL0.2086 mL0.4171 mL2.0856 mL
100 mM0.0209 mL0.1043 mL0.2086 mL1.0428 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

HPPE1HBenzimidazole5carboxamide,N[2(2hydroxyethoxy)ethyl]1methyl2[[6(trifluoromethyl)2benzothiazolyl]amino]
Related Tags: buy HPPE | purchase HPPE | HPPE cost | order HPPE | HPPE chemical structure | HPPE formula | HPPE molecular weight
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