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IL-13 Protein, Human, Recombinant (His)

TargetMol | SPR
Catalog No. TMPJ-00575 Copy Product Info
IL-13 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 13-30 KDa and the accession number is AAH96139.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$74-In Stock
10 μg$118In StockIn Stock
20 μg$1877-10 days7-10 days
50 μg$350-In Stock
100 μg$4977-10 days7-10 days
200 μg$7387-10 days7-10 days
500 μg$1,2207-10 days7-10 days
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In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
For research use only—not for human use. No sales to individuals. Use as intended only.
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Biological Activity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 1.5-4.5 ng/ml. (QC verified)
IL-13 Protein, Human, Recombinant (His)
Description
IL-13 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 13-30 KDa and the accession number is AAH96139.
Species
Human
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberP35225
Synonyms
Interleukin-13,IL-13
Amino Acid
Gly35-Asn146
Construction
Gly35-Asn146
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
IL-13 Protein, Human, Recombinant (His)
Molecular Weight13-30 KDa (reducing condition)
Endotoxin< 10 EU/µg as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background
Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.

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