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Synonyms: SDR27X1, OA-519, fatty acid synthase, FAS

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $296 | 7-10 days | 7-10 days | |
| 100 μL | $489 | 7-10 days | 7-10 days |
| Description | Anti-FASN Antibody (1K266) is a Mouse antibody targeting FASN. Anti-FASN Antibody (1K266) can be used in ICC/IF,IF,IHC-Fr,IHC-P,WB. |
| Synonyms | SDR27X1, OA-519, fatty acid synthase, FAS |
| Ig Type | IgG1, κ |
| Clone | 1K266 |
| Reactivity | Human (predicted:Mouse) |
| Application | |
| Recommended Dose | WB: 1:500-5000; IHC-P: 1:100-500; IHC-Fr: 1:20-200; ICC/IF: 1:100-500; IF: 1:20-200 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
| Tissue Specificity | Ubiquitous. Prominent expression in brain, lung, and liver. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Affinity purified by Protein AGL |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | FASN (Fatty Acid Synthase) is a central enzyme in de novo lipogenesis. FAS is a target for SREBP and is upregulated by LXR activation; it is also one of the accepted markers for insulin resistance, SREBP and LXR activation. |
| Immunogen | KLH conjugated synthetic peptide: human FASN |
| Antigen Species | Human |
| Gene Name | FASN |
| Gene ID | |
| Protein Name | Fatty acid synthase |
| Uniprot ID | |
| Biology Area | Integration of energy metabolism,Metabolism of lipids and lipoproteins,Enzymes,Synthesis,Energy Metabolism,Integration of energy,Lipid metabolism,Fatty acid oxidation,Cancer,Obesity,Metabolism,Energy Metabolism,Lipid metabolism |
| Function | Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein. |
| Molecular Weight | Theoretical: 274 kDa. Actual: 270 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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