store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 125.00 | |
10 mg | In stock | $ 188.00 | |
50 mg | In stock | $ 470.00 |
Description | Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5. |
Targets&IC50 | Glucose uptake:130 μM |
In vitro | Dehydro nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM[1]. |
Synonyms | BAY-b 4759 |
Molecular Weight | 344.32 |
Formula | C17H16N2O6 |
CAS No. | 67035-22-7 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 2.7 mg/mL (7.8 mM)
DMSO: 27.0 mg/mL (78.5 mM)
DMF: 30 mg/mL
DMSO:PBS (pH 7.2) (1:10): 0.1 mg/mL
You can also refer to dose conversion for different animals. More
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Dehydro Nifedipine 67035-22-7 BAY-b 4759 inhibitor inhibit