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Tenascin Protein, Human, Recombinant (His)

(Synonyms: TN-C, TNC, TN, Tenascin-C, Hxb, Hexabrachion) Copy Product Info

Synonyms: TN-C, TNC, TN, Tenascin-C, Hxb, Hexabrachion

Catalog No. TMPK-01392 Copy Product Info
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tenascin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 65.27 kDa and the accession number is P24821-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$51-In Stock
10 μg$807-10 days7-10 days
20 μg$129-In Stock
50 μg$248-In Stock
100 μg$418In StockIn Stock
200 μg$7577-10 days7-10 days
500 μg$1,6707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:> 95%
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Description
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates, and molecular phylogeny indicates that it evolved before fibronectin. Tenascin-C has many extracellular binding partners, including matrix components, soluble factors and pathogens; it also influences cell phenotype directly through interactions with cell surface receptors. Tenascin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 65.27 kDa and the accession number is P24821-1.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberP24821-1
ConstructionGly23-Ser621
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
https://cdn.targetmol.com/group3/M00/3E/DF/CgoaEWbGogqEMSeuAAAAAP9ylYE817.png,https://cdn.targetmol.com/group3/M00/3E/DF/CgoaEWbGogqEaI9jAAAAAFUqsrk300.png
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsTN-C, TNC, TN, Tenascin-C, Hxb, Hexabrachion
Research Background
Chemical Properties
Molecular Weight65.27 kDa (predicted). Due to glycosylation, the protein migrates to 66-70 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Related Tags: Tenascin Protein, Human, Recombinant (His) chemical structure | Tenascin Protein, Human, Recombinant (His) molecular weight