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L-Ascorbic acid 2-phosphate
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Catalog No. T19390Cas No. 23313-12-4
Alias 2-Phospho-L-ascorbic acid
L-ascorbic acid 2-phosphate (Vitamin C phosphate) is a stable and long-lasting vitamin C derivative that stimulates collagen formation and has potential antioxidant capacity. L-ascorbic acid 2-phosphate is commonly used to promote osteogenic differentiation of human adipose stem cells (hASCs) in cell culture by increasing alkaline phosphatase (ALP) activity and runt-related transcription factor-2-DNA(runx2A) expression.
L-Ascorbic acid 2-phosphate
😃Good
Purity: 99.99%
Catalog No. T19390Alias 2-Phospho-L-ascorbic acidCas No. 23313-12-4
L-ascorbic acid 2-phosphate (Vitamin C phosphate) is a stable and long-lasting vitamin C derivative that stimulates collagen formation and has potential antioxidant capacity. L-ascorbic acid 2-phosphate is commonly used to promote osteogenic differentiation of human adipose stem cells (hASCs) in cell culture by increasing alkaline phosphatase (ALP) activity and runt-related transcription factor-2-DNA(runx2A) expression.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 mg | $30 | In Stock | In Stock | |
| 500 mg | $37 | In Stock | In Stock | |
| 1 g | $51 | In Stock | In Stock | |
| 5 g | $116 | - | In Stock | |
| 10 g | $170 | 1-2 weeks | 1-2 weeks |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.99%
Appearance:Solid
Color:White to Brown
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | L-ascorbic acid 2-phosphate (Vitamin C phosphate) is a stable and long-lasting vitamin C derivative that stimulates collagen formation and has potential antioxidant capacity. L-ascorbic acid 2-phosphate is commonly used to promote osteogenic differentiation of human adipose stem cells (hASCs) in cell culture by increasing alkaline phosphatase (ALP) activity and runt-related transcription factor-2-DNA(runx2A) expression. |
| In vitro | L-Ascorbic acid 2-phosphate (0.1-1.5 mM, every 2-3 days for 2-3 weeks) significantly stimulated cell growth, whereas addition of L-ascorbic acid (Asc) only achieved weak growth stimulation. [1] L-Ascorbic acid 2-phosphate (50 μM-250 μM) is required for efficient osteogenic differentiation of human adipose-derived stem cells (hASCs), and higher concentrations of AsA2-P lead to increased runx2 expression and ALP activity. [3] |
| Synonyms | 2-Phospho-L-ascorbic acid |
| Molecular Weight | 256.1 |
| Formula | C6H9O9P |
| Cas No. | 23313-12-4 |
| Smiles | O(P(=O)(O)O)C1=C(O)[C@@]([C@H](CO)O)(OC1=O)[H] |
| Relative Density. | 2.01 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: < 1 mg/mL (insoluble) 1 M HCl: 20 mg/mL (78.09 mM), Sonication is recommended. 0.1 M HCl: 10 mg/mL (39.05 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
0.1 M HCl/1 M HCl
1 M HCl
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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