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L-DOPA methyl ester (hydrochloride)

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Catalog No. T7654Cas No. 1421-65-4

L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.

L-DOPA methyl ester (hydrochloride)

L-DOPA methyl ester (hydrochloride)

🥰Excellent
Purity: 99.81%
Catalog No. T7654Cas No. 1421-65-4
L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.
Pack SizePriceAvailabilityQuantity
5 mg$33In Stock
10 mg$47In Stock
25 mg$77In Stock
50 mg$118In Stock
100 mg$192In Stock
200 mg$285In Stock
500 mg$482In Stock
1 mL x 10 mM (in DMSO)$39In Stock
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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Purity:99.81%
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Product Introduction

Bioactivity
Description
L-DOPA methyl ester (LDME) is an agonist of dopamine D1 receptor.
In vitro
L-DOPA methyl ester (LDME) might ameliorate the functional cytoarchitecture in visual cortex area 17 through mechanisms that elevate DA content and increase endogenous c-fos expression, as well as inhibit neuronal lesion in visual cortex tissue
Chemical Properties
Molecular Weight247.675
FormulaC10H14ClNO4
Cas No.1421-65-4
SmilesCl.COC(=O)[C@@H](N)Cc1ccc(O)c(O)c1
Relative Density.1.322g/cm3
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (111.03 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.0375 mL20.1877 mL40.3755 mL201.8775 mL
5 mM0.8075 mL4.0375 mL8.0751 mL40.3755 mL
10 mM0.4038 mL2.0188 mL4.0375 mL20.1877 mL
20 mM0.2019 mL1.0094 mL2.0188 mL10.0939 mL
50 mM0.0808 mL0.4038 mL0.8075 mL4.0375 mL
100 mM0.0404 mL0.2019 mL0.4038 mL2.0188 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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