Powder: -20°C for 3 years | In solvent: -80°C for 1 year
icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 290.00 | |
5 mg | In stock | $ 664.00 | |
10 mg | In stock | $ 930.00 | |
25 mg | In stock | $ 1,310.00 | |
50 mg | In stock | $ 1,640.00 | |
100 mg | In stock | $ 1,995.00 |
Description | icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases. |
In vitro | icFSP1(5 µM) triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation before ferroptosis induction, in synergism with GPX4 inhibition[1]. |
In vivo | In a tumour-bearing mouse model, icFSP1(i.p.) significantly inhibited tumour growth and decreased tumour weight, without affecting body weight. icFSP1 markedly increased the abundance of hFSP1 condensates and immunoreactivity to 4-hydroxynonenal, a lipid peroxidation breakdown product[1]. |
Molecular Weight | 459.49 |
Formula | C26H25N3O5 |
CAS No. | 1115910-36-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (119.7 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
icFSP1 1115910-36-5 Apoptosis inhibitor inhibit