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Tirzepatide monosodium salt
🥰Excellent
Catalog No. TP1111L1
Alias Tirzepatide sodium salt(2023788-19-2 free base), LY-3298176 sodium salt
Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.
Tirzepatide monosodium salt
🥰Excellent
Purity: 99.69%
Catalog No. TP1111L1Alias Tirzepatide sodium salt(2023788-19-2 free base), LY-3298176 sodium salt
Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $263 | In Stock | In Stock | |
| 5 mg | $689 | In Stock | In Stock | |
| 10 mg | $1,130 | In Stock | In Stock | |
| 25 mg | $1,690 | In Stock | In Stock | |
| 50 mg | $2,320 | In Stock | In Stock | |
| 100 mg | $3,130 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.69%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity. |
| In vitro | Under high glucose-induced conditions, treatment of SHSY5Y cells with Tirzepatide sodium salt at concentrations ranging from 0 to 0.4 μM for 7 days resulted in significant upregulation of CREB and BDNF mRNA expression. Additionally, it increased the protein levels of pAkt, MAP2, GAP43, AGBL4, GLUT4, SORBS1, and Bcl-2 while decreasing the protein level of BAX[1]. |
| In vivo | In diet-induced obese (DIO) mice, Tirzepatide sodium salt (10 nM/kg, subcutaneous injection) reduced body weight and food consumption. It decreased glucose, insulin, leptin, and C-peptide levels[2]. |
| Synonyms | Tirzepatide sodium salt(2023788-19-2 free base), LY-3298176 sodium salt |
| Molecular Weight | 4835.51 |
| Formula | C225H347N48O68Na |
| Smiles | OC[C@H](NC([C@H]1N(CCC1)C([C@H]2N(CCC2)C([C@H]3N(CCC3)C([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H]4N(CCC4)C(CNC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(C(C)(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC(C(C)(NC([C@@H](N)CC5=CC=C(C=C5)O)=O)C)=O)CCC(O)=O)=O)=O)[C@@H](C)O)=O)CC6=CC=CC=C6)=O)[C@@H](C)O)=O)CO)=O)CC(O)=O)=O)CC7=CC=C(C=C7)O)=O)CO)=O)[C@H](CC)C)=O)C)=O)CC(C)C)=O)CC(O)=O)=O)CCCCN)=O)[C@H](CC)C)=O)C)=O)CCC(N)=O)=O)CCCCNC(COCCOCCNC(COCCOCCNC(CC[C@H](NC(CCCCCCCCCCCCCCCCCCC([O-])=O)=O)C(O)=O)=O)=O)=O)=O)C)=O)CC8=CC=CC=C8)=O)C(C)C)=O)CCC(N)=O)=O)CC9=CNC%10=C9C=CC=C%10)=O)CC(C)C)=O)[C@H](CC)C)=O)C)=O)=O)=O)=O)CO)=O)CO)=O)=O)C)=O)=O)=O)=O)C(N)=O.[Na+] |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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