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Anti-CD31/PECAM-1 Antibody-APC (8O85)
🥰Excellent
Catalog No. TMAY-00348A
Anti-CD31/PECAM-1 Antibody-APC (8O85) is a APC-conjugated Mouse antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody-APC (8O85) can be used in FCM.
Anti-CD31/PECAM-1 Antibody-APC (8O85)
Anti-CD31/PECAM-1 Antibody-APC (8O85)
🥰Excellent
Catalog No. TMAY-00348A
Anti-CD31/PECAM-1 Antibody-APC (8O85) is a APC-conjugated Mouse antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody-APC (8O85) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD31/PECAM-1 Antibody-APC (8O85) is a APC-conjugated Mouse antibody targeting CD31/PECAM-1. Anti-CD31/PECAM-1 Antibody-APC (8O85) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 8O85 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD31 expression. Profile of human whole blood monocytes (left panel) and granulocyte (right panel) analyzed on a FACSCalibur (BDIS, San Jose, CA). The histogram were derived from the gated events based on light scattering characteristics of monocytes and granulocytes. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD31 / PECAM1 (rh CD31 / PECAM1; TMPY-00970; EAW94208.1; Met 1-Lys 601) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | The Cluster of Differentiation 31 (CD31) adhesion molecule, also known as platelet-endothelial cell adhesion molecule-1 (PECAM-1), is the only known member of the CAM family on platelets. CD31 protein is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, monocytes, neutrophils, and certain T cell subsets. CD31 protein is also expressed in certain tumors, including epithelioid hemangioendothelioma, other vascular tumors, and histiocytic malignancies. CD31 plays a key role in removing aged neutrophils and tissue regeneration. CD31 protein mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human CD31 / PECAM1 protein (TMPY-00970) |
| Antigen Species | Human |
| Biology Area | Hemangioblast Markers, ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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