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Cloprostenol sodium salt

Name: Cloprostenol sodium salt
Brand: TargetMol
SKU: T5847
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5847Cas No. 55028-72-3

Alias ICI 80996 sodium salt, DL-Cloprostenol sodium, Cloprostenol sodium

Cloprostenol sodium salt (ICI 80996 sodium salt) is a more water-soluble, crystalline form of cloprostenol compared to the free acid and is a synthetic analog of prostaglandin F2α.

Cloprostenol sodium salt

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Purity: 98.47%

Catalog No. T5847Alias ICI 80996 sodium salt, DL-Cloprostenol sodium, Cloprostenol sodiumCas No. 55028-72-3

Cloprostenol sodium salt (ICI 80996 sodium salt) is a more water-soluble, crystalline form of cloprostenol compared to the free acid and is a synthetic analog of prostaglandin F2α.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$45	In Stock	In Stock
5 mg	$106	In Stock	In Stock
10 mg	$172	In Stock	In Stock
25 mg	$347	In Stock	In Stock
50 mg	$513	In Stock	In Stock
100 mg	$737	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98.47%

Color:White

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COA HNMR LCMS

Product Introduction

Cloprostenol sodium salt AI Summary

Cloprostenol sodium salt inhibits the activities of human BSEP, MRP2, and MRP3 with high IC50 values (>133000.0 nM) in membrane vesicle transport assays, indicating low inhibition potency towards these transporters. However, it exhibits a significantly stronger inhibitory activity against human MRP4 with an IC50 value of 1900.0 nM..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Cloprostenol sodium salt (ICI 80996 sodium salt) is a more water-soluble, crystalline form of cloprostenol compared to the free acid and is a synthetic analog of prostaglandin F2α.
Synonyms	ICI 80996 sodium salt, DL-Cloprostenol sodium, Cloprostenol sodium

Chemical Properties

Molecular Weight	446.9
Formula	C₂₂H₂₈ClNaO₆
Cas No.	55028-72-3
Smiles	[Na+].O[C@H](COc1cccc(Cl)c1)\C=C\[C@@H]1[C@@H](O)C[C@@H](O)[C@H]1C\C=C/CCCC([O-])=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 115 mg/mL (257.33 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	2.2376 mL	11.1882 mL	22.3764 mL	111.8819 mL
5 mM	0.4475 mL	2.2376 mL	4.4753 mL	22.3764 mL
10 mM	0.2238 mL	1.1188 mL	2.2376 mL	11.1882 mL
20 mM	0.1119 mL	0.5594 mL	1.1188 mL	5.5941 mL
50 mM	0.0448 mL	0.2238 mL	0.4475 mL	2.2376 mL
100 mM	0.0224 mL	0.1119 mL	0.2238 mL	1.1188 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc