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PEG-8 laurate

Catalog No. T40438 CAS 35179-86-3

PEG-8 laurate is a monofunctional surfactant and skin penetration enhancer. It disrupts the skin barrier and facilitates the formation of elastic vesicles when synthesized.

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PEG-8 laurate, CAS 35179-86-3

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25 mg	Inquiry	$ 1,520.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	PEG-8 laurate is a monofunctional surfactant and skin penetration enhancer. It disrupts the skin barrier and facilitates the formation of elastic vesicles when synthesized.
In vivo	Pretreatment of hairless mouse skin using elastic vesicles that contain 70 mol% PEG-8 laurate enhances the diffusion of 3 H 2 O[1].

Molecular Weight	552.746
Formula	C28H56O10
CAS No.	35179-86-3

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

References and Literature

1. Bergh BA, et, al. Elasticity of vesicles affects hairless mouse skin structure and permeability. J Control Release. 1999 Dec 6;62(3):367-79. 2. Barbosa RM, et, al. Physicochemical characterization of surfactant incorporating vesicles that incorporate colloidal magnetite. J Liposome Res. 2013 Mar;23(1):47-53.

Dose Conversion

You can also refer to dose conversion for different animals. More

In vivo Formulation Calculator (Clear solution)

Step One: Enter information below

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Step Two: Enter the in vivo formulation

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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The answer of 19.713 mg appears in the Mass box

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What volume of a given 10 mM stock solution is required to make 20ml of a 50 μM solution?
Using the equation C1V1 = C2V2, where C1=10 mM, C2=50 μM, V2=20 ml and V1 is the unknown:
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The answer of 100 microliter (0.1 ml) appears in the Volume (start) box

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

PEG-8 laurate 35179-86-3 PEG 8 laurate PEG8 laurate inhibitor inhibit

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.