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CPUY192018

Name: CPUY192018
Brand: TargetMol
SKU: T27077
Price: 52 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T27077Cas No. 1567836-15-0

Alias CPUY192018 Na2, CPUY-192018

CPUY192018 is an inhibitor of Keap1-Nrf2 protein-protein interactions and shows cytoprotective effects in NCM460 colon cells.CPUY192018 inhibits glycolysis, enhances resistance to oxidative stress, and can be used to study mitochondrial autophagy.

CPUY192018

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Purity: 98.9%

Catalog No. T27077Alias CPUY192018 Na2, CPUY-192018Cas No. 1567836-15-0

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$52	In Stock	In Stock
5 mg	$123	In Stock	In Stock
10 mg	$198	In Stock	In Stock
25 mg	$455	-	In Stock
50 mg	$689	-	In Stock
100 mg	$1,090	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.9%

Appearance:Solid

Color:White

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	CPUY192018 is an inhibitor of Keap1-Nrf2 protein-protein interactions and shows cytoprotective effects in NCM460 colon cells.CPUY192018 inhibits glycolysis, enhances resistance to oxidative stress, and can be used to study mitochondrial autophagy.
Targets&IC50	Keap1-Nrf2-ARE:0. 0.63 µM
Synonyms	CPUY192018 Na2, CPUY-192018

Chemical Properties

Molecular Weight	614.64
Formula	C₂₈H₂₆N₂O₁₀S₂
Cas No.	1567836-15-0
Smiles	O=C(O)CN(C=1C=CC(=C2C=CC=CC21)N(CC(=O)O)S(=O)(=O)C3=CC=C(OC)C=C3)S(=O)(=O)C4=CC=C(OC)C=C4
Relative Density.	1.502 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (325.39 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6270 mL	8.1348 mL	16.2697 mL	81.3484 mL
5 mM	0.3254 mL	1.6270 mL	3.2539 mL	16.2697 mL
10 mM	0.1627 mL	0.8135 mL	1.6270 mL	8.1348 mL
20 mM	0.0813 mL	0.4067 mL	0.8135 mL	4.0674 mL
50 mM	0.0325 mL	0.1627 mL	0.3254 mL	1.6270 mL
100 mM	0.0163 mL	0.0813 mL	0.1627 mL	0.8135 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc