Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

DCVC

Copy Product Info
😃Good
Catalog No. T36401Cas No. 13419-46-0

DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.

DCVC

DCVC

Copy Product Info
😃Good
Catalog No. T36401Cas No. 13419-46-0
DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$2755 days5 days
5 mg$3475 days5 days
10 mg$5415 days5 days
1 mL x 10 mM (in DMSO)$3825 days5 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Resource Download

Product Introduction

Bioactivity
Description
DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.
In vitro
In vitro, DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 μM) significantly inhibits LTA-, LPS-, and GBS-stimulated cytokine release from tissue cultures as early as 4 h (P ≤ 0.05). In contrast, TCA (up to 500 μM) does not inhibit LTA-stimulated cytokine release from tissue punches. DCVC effects on LTA-stimulated and LPS-stimulated TNF-α release from tissue punch cultures of extraplacental membranes. DCVC effects on GBS-stimulated release of pro-inflammatory cytokines from extraplacental membranes in transwell cultures.
Chemical Properties
Molecular Weight216.09
FormulaC5H7Cl2NO2S
Cas No.13419-46-0
SmilesN[C@@H](CS\C(Cl)=C/Cl)C(O)=O
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 23 mg/mL (106.44 mM), Sonication is recommended.
H2O: 1.03 mg/mL (4.77 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM4.6277 mL23.1385 mL46.2770 mL231.3851 mL
DMSO
1mg5mg10mg50mg
5 mM0.9255 mL4.6277 mL9.2554 mL46.2770 mL
10 mM0.4628 mL2.3139 mL4.6277 mL23.1385 mL
20 mM0.2314 mL1.1569 mL2.3139 mL11.5693 mL
50 mM0.0926 mL0.4628 mL0.9255 mL4.6277 mL
100 mM0.0463 mL0.2314 mL0.4628 mL2.3139 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DCVC
Related Tags: buy DCVC | purchase DCVC | DCVC cost | order DCVC | DCVC chemical structure | DCVC in vitro | DCVC formula | DCVC molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.