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Tri-(PEG1-C2-acid) is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Tri-(PEG1-C2-acid) is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are compounds consisting of two ligands joined by a linker: one ligand targets an E3 ubiquitin ligase and the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 365.38 |
Formula | C15H27NO9 |
Cas No. | 1381861-95-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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