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CD79B Protein, Mouse, Recombinant (hFc)

Catalog No. TMPJ-00862
Synonyms: Ig-Beta, B-Cell-Specific Glycoprotein B29, B29, B-Cell Antigen Receptor Complex-Associated Protein Beta Chain, IGB, Ig-β, CD79B, Immunoglobulin-Associated B29 Protein, B-Cell Antigen Receptor Complex-Associated Protein β Chain

CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CD79B Protein, Mouse, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 137.00
50 μg 5 days $ 539.00
500 μg 5 days $ 2,070.00
1 mg 5 days $ 3,100.00
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Biological Description
Technical Params
Product Properties
Description CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.
Species Mouse
Expression System Human Cells
Tag C-Fc
Accession Number P15530
Synonyms Ig-Beta, B-Cell-Specific Glycoprotein B29, B29, B-Cell Antigen Receptor Complex-Associated Protein Beta Chain, IGB, Ig-β, CD79B, Immunoglobulin-Associated B29 Protein, B-Cell Antigen Receptor Complex-Associated Protein β Chain
Amino Acid Val26-Asp158
Construction Recombinant Mouse CD79B is produced by our Mammalian expression system and the target gene encoding Val26-Asp158 is expressed with a human IgG1 Fc tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 50-65 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background CD79B is a single-pass type I membrane protein. CD79B contains one Ig-like V-type domain and one ITAM domain. CD79B is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR), which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79B enhances phosphorylation of CD79A, possibly by recruiting kinases that phosphorylate CD79A or by recruiting proteins that bind to CD79A and protect it from dephosphorylation.

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Keywords

CD79B Protein, Mouse, Recombinant (hFc) B-29 Ig-Beta B-Cell-Specific Glycoprotein B29 B29 B 29 B-Cell Antigen Receptor Complex-Associated Protein Beta Chain IGB Ig-β CD79B Immunoglobulin-Associated B29 Protein B-Cell Antigen Receptor Complex-Associated Protein β Chain recombinant recombinant-proteins proteins protein

 

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