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2-O-trans-p-Coumaroylalphitolic acid (Zj7), a triterpene sourced from jujube plants, functions as a selective modulator of the glucocorticoid receptor (GR). This compound holds potential for use in obesity research [1].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | 2-O-trans-p-Coumaroylalphitolic acid (Zj7), a triterpene sourced from jujube plants, functions as a selective modulator of the glucocorticoid receptor (GR). This compound holds potential for use in obesity research [1]. |
| In vivo | Administered at a dose of 50 mg/kg via intraperitoneal injection daily for two weeks, 2-O-trans-p-Coumaroylalphitolic acid shows anti-obesity effects in both high-fat diet-induced obese (DIO) mice and db/db mice [1]. The compound also improves insulin sensitivity and reduces the expression of Agrp, Npy, and Cdkn1a in the ARC. |
| Molecular Weight | 618.84 |
| Formula | C39H54O6 |
| Cas No. | 67911-63-1 |
| Smiles | C(O)(=O)[C@]12[C@@]([C@@]3([C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)[C@@H](O)[C@H](OC(/C=C/C6=CC=C(O)C=C6)=O)C5)[H])[H])[H])([C@H](C(C)=C)CC2)[H] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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