CD163 Protein, Human, Recombinant (His & Avi), Biotinylated

The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation.

Pack Size	Availability	Price/USD
100 μg	5 days	$ 814.00
500 μg	5 days	$ 3,250.00
1 mg	5 days	$ 5,440.00

Pack Size

Availability

Price/USD

Quantity

100 μg

5 days

$ 814.00

500 μg

5 days

$ 3,250.00

1 mg

5 days

$ 5,440.00

Description

Species	Human
Expression System	HEK293
Tag	C-His-Avi
Accession Number	Q86VB7-1
Synonyms	HbSR, sCD163, M130, GHI/61, MM130, CD163 molecule, CD163, RM3/1, SCARI1
Construction	Recombinant Biotinylated Human CD163 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Ser42-Ser1045.[Accession \|Q86VB7-1]
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight	The protein has a predicted MW of 111.4 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Tris-Bis PAGE result.

Endotoxin	Less than 1EU per μg by the LAL method.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage	-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background	The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation.