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8-Oxoepiberberine

Name: 8-Oxoepiberberine
Brand: TargetMol
SKU: TN2023
Price: 68 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2023Cas No. 19716-60-0

Alias Oxyepiberberine

8-Oxoepiberberine (Oxyepiberberine) is an alkaloid metabolite in the plasma after oral administration of Zuojin formula. Zuojin formula is a traditional chinese medicine used to treat gastrointestinal disease.

8-Oxoepiberberine

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Purity: 99.681%

Catalog No. TN2023Alias OxyepiberberineCas No. 19716-60-0

Pack Size	Price	Availability
1 mg	$68	In Stock
5 mg	$163	In Stock
10 mg	$263	In Stock
25 mg	$446	In Stock
50 mg	$645	In Stock
100 mg	$886	In Stock

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Batch Information

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Purity:99.681%

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COA LCMS

Product Introduction

Bioactivity

Description	8-Oxoepiberberine (Oxyepiberberine) is an alkaloid metabolite in the plasma after oral administration of Zuojin formula. Zuojin formula is a traditional chinese medicine used to treat gastrointestinal disease.
Synonyms	Oxyepiberberine

Chemical Properties

Molecular Weight	351.35
Formula	C₂₀H₁₇NO₅
Cas No.	19716-60-0
Smiles	COc1cc2CCn3c(cc4ccc5OCOc5c4c3=O)-c2cc1OC
Relative Density.	1.44 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mg/mL (28.46 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8462 mL	14.2308 mL	28.4616 mL	142.3082 mL
5 mM	0.5692 mL	2.8462 mL	5.6923 mL	28.4616 mL
10 mM	0.2846 mL	1.4231 mL	2.8462 mL	14.2308 mL
20 mM	0.1423 mL	0.7115 mL	1.4231 mL	7.1154 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc