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Anti-Collagen II/COL2A1 Polyclonal Antibody 2

(Synonyms: STL1, SEDC, collagen, type II, α1, collagen, type II, alpha 1, COL11A3, AOM, ANFH) Copy Product Info
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Synonyms: STL1, SEDC, collagen, type II, α1, collagen, type II, alpha 1, COL11A3, AOM, ANFH

Catalog No. TMAB-00458 Copy Product Info
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Anti-Collagen II/COL2A1 Polyclonal Antibody 2 is a Rabbit antibody targeting Collagen II/COL2A1. Anti-Collagen II/COL2A1 Polyclonal Antibody 2 can be used in IF,IHC-Fr,IHC-P,WB.
Anti-Collagen II/COL2A1 Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Collagen II/COL2A1 Polyclonal Antibody 2 is a Rabbit antibody targeting Collagen II/COL2A1. Anti-Collagen II/COL2A1 Polyclonal Antibody 2 can be used in IF,IHC-Fr,IHC-P,WB.
SynonymsSTL1, SEDC, collagen, type II, α1, collagen, type II, alpha 1, COL11A3, AOM, ANFH
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted, extracellular space, extracellular matrix.
Tissue SpecificityIsoform 2 is highly expressed in juvenile chondrocyte and low in fetal chondrocyte.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Collagen II
Antigen Species
Human
Gene Name
COL2A1
Gene ID
Protein Name
Procollagen Type II N-Terminal Propeptide
Uniprot ID
Function
Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.
Chemical Properties
Molecular WeightTheoretical: 117 kDa. Actual: 125-135 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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