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Flurbiprofen Axetil

Name: Flurbiprofen Axetil
Brand: TargetMol
SKU: T3500
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3500Cas No. 91503-79-6

Alias Ropiopn, Ropion, Lipfen

Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.

Flurbiprofen Axetil

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Purity: 98%

Catalog No. T3500Alias Ropiopn, Ropion, LipfenCas No. 91503-79-6

Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$33	In Stock	In Stock
25 mg	$58	In Stock	In Stock
50 mg	$98	In Stock	In Stock
100 mg	$153	In Stock	In Stock
200 mg	$227	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:98%

Color:Transparent

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Product Introduction

Flurbiprofen Axetil AI Summary

Flurbiprofen Axetil exhibits significant bioactivity, primarily noted for its potential antiviral properties against the Ebola virus, demonstrating potency with AC50 values of 1778.3 nM and 1.778 µM in respective screening assays. However, it shows low efficacy in inhibiting SARS-CoV-2-infected Vero E6 cell viability, with an inhibition index of 0.07084 compared to the arbidol control. Beyond its antiviral potential, Flurbiprofen Axetil binds to multiple receptors, including DRD1, SLC6A3, ESR1, and others, and exhibits diverse pharmacological activities. It acts as an antagonist at TBXA2R, CHRM1, and ADRA1A receptors, and as an agonist at HTR2B, ADRA1A, CHRM1, and TBXA2R receptors. Additionally, the compound inhibits enzymes such as KCNH2, ACHE, MAOA, KDR, PDE3A, PTGS1, and PDE4A, demonstrating its broad spectrum of bioactivities..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.
Synonyms	Ropiopn, Ropion, Lipfen

Chemical Properties

Molecular Weight	330.35
Formula	C₁₉H₁₉FO₄
Cas No.	91503-79-6
Smiles	CC(OC(C)=O)OC(=O)C(C)c1ccc(c(F)c1)-c1ccccc1
Relative Density.	1.169g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (136.22 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0271 mL	15.1355 mL	30.2709 mL	151.3546 mL
5 mM	0.6054 mL	3.0271 mL	6.0542 mL	30.2709 mL
10 mM	0.3027 mL	1.5135 mL	3.0271 mL	15.1355 mL
20 mM	0.1514 mL	0.7568 mL	1.5135 mL	7.5677 mL
50 mM	0.0605 mL	0.3027 mL	0.6054 mL	3.0271 mL
100 mM	0.0303 mL	0.1514 mL	0.3027 mL	1.5135 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc