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Anti-CD204/MSR1 Antibody-PE (4Z10)
🥰Excellent
Catalog No. TMAY-03126P
Anti-CD204/MSR1 Antibody-PE (4Z10) is a PE-conjugated Rabbit antibody targeting CD204/MSR1. Anti-CD204/MSR1 Antibody-PE (4Z10) can be used in FCM.
Anti-CD204/MSR1 Antibody-PE (4Z10)
Anti-CD204/MSR1 Antibody-PE (4Z10)
🥰Excellent
Catalog No. TMAY-03126P
Anti-CD204/MSR1 Antibody-PE (4Z10) is a PE-conjugated Rabbit antibody targeting CD204/MSR1. Anti-CD204/MSR1 Antibody-PE (4Z10) can be used in FCM.
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Product Introduction
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Chemical Properties
| Description | Anti-CD204/MSR1 Antibody-PE (4Z10) is a PE-conjugated Rabbit antibody targeting CD204/MSR1. Anti-CD204/MSR1 Antibody-PE (4Z10) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 4Z10 |
| Reactivity | Mouse |
| Verified Activity | Profile of anti-MSR1 (CD204) reactivity on Raw264.7 cells analyzed by flow cytometry. Cells should be Fc-blocked by treatment with Mouse BD Fc Block™ purified anti-CD16/CD32 mAb 2.4G2 prior to staining, washed, then stained with PE Rabbit anti-MSR1 (CD204). |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse MSR1 / CD204 (rM MSR1 / CD204; TMPY-00528; AAH03814.1; Trp 83-Val 354) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Macrophage scavenger receptor types I and II, also known as Macrophage acetylated LDL receptor I and II, Scavenger receptor class A member 1, CD24, MSR1, and SCARA1, is a single-pass type II membrane protein that contains one collagen-like domain and one SRCR domain. Macrophages are distributed in all peripheral tissues and play a critical role in the first line of the innate immune defenses against bacterial infection by phagocytosis of bacterial pathogens through the macrophage scavenger receptor 1 (MSR1). MSR1 / SCARA1 is one of the membrane glycoproteins implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis. Two types of receptor subunits exist. These receptors mediate the endocytosis of a diverse group of macromolecules, including modified low-density lipoproteins (LDL). MSR1 / SCARA1 is also involved in chronic inflammation which is a risk factor for prostate cancer. MSR1 1 gene was identified as a candidate susceptibility gene for hereditary prostate cancer and as a risk factor for sporadic prostate cancer. |
| Conjucates | PE |
| Others Formats | Unconjugated/FITC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Mouse MSR1 / CD204 protein (TMPY-00528) |
| Antigen Species | Mouse |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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