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Anti-OSMR Antibody-APC (5Q467) (Synonyms: OSMRB, oncostatin M receptor)

Catalog No. TMAY-01775A Copy Product Info
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Anti-OSMR Antibody-APC (5Q467) is a APC-conjugated Rabbit antibody targeting OSMR. Anti-OSMR Antibody-APC (5Q467) can be used in FCM.

Anti-OSMR Antibody-APC (5Q467)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01775A
Synonyms OSMRB, oncostatin M receptor

Anti-OSMR Antibody-APC (5Q467) is a APC-conjugated Rabbit antibody targeting OSMR. Anti-OSMR Antibody-APC (5Q467) can be used in FCM.

Anti-OSMR Antibody-APC
(5Q467)
Pack SizePriceUSA StockGlobal StockQuantity
25 T$1277-10 days7-10 days
100 T$2567-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-OSMR Antibody-APC (5Q467) is a APC-conjugated Rabbit antibody targeting OSMR. Anti-OSMR Antibody-APC (5Q467) can be used in FCM.
SynonymsOSMRB, oncostatin M receptor
Ig Type
Rabbit IgG
Clone
5Q467
Reactivity
Human
Specificity
Human OSMR
Verified Activity
Flow cytometric analysis of Human OSMR expression in HeLa cells.
Application
FCM
Recommended Dose
10 μl/Test, 0.1 mg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human OSMR / IL-31RB (rh OSMR / IL-31RB; TMPY-01305; NP_003990.1; Met1-Met740) and conjugated with APC under optimum conditions, the unreacted APC was removed.
PurificationProtein A
AppearanceLiquid
FormulationPBS solution containing 0.5% BSA and 0.03%ProClin300
Research BackgroundOncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the type I cytokine receptor family. IL-31RB/OSMR heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in IL-31RB/OSMR have been associated with familial primary localized cutaneous amyloidosis. Defects in IL-31RB/OSMR are the cause of amyloidosis primary localized cutaneous type 1 (PLCA1), also known as familial lichen amyloidosis of familial cutaneous lichen amyloidosis. PLCA1 is hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening (lichenification) that may be exacerbated by chronic scratching and rubbing. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins.
Related Conjugates and Formulations
Conjucates
APC
Others Formats
Unconjugated/PE
Antibody Types Available
3
Antigen Details
Immunogen
Recombinant Protein: Human OSMR / IL-31RB protein (TMPY-01305)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
TransportShipping with blue ice.

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