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Anti-OSMR Antibody-APC (5Q467)
🥰Excellent
Catalog No. TMAY-01775A
Anti-OSMR Antibody-APC (5Q467) is a APC-conjugated Rabbit antibody targeting OSMR. Anti-OSMR Antibody-APC (5Q467) can be used in FCM.
Anti-OSMR Antibody-APC (5Q467)
Anti-OSMR Antibody-APC (5Q467)
🥰Excellent
Catalog No. TMAY-01775A
Anti-OSMR Antibody-APC (5Q467) is a APC-conjugated Rabbit antibody targeting OSMR. Anti-OSMR Antibody-APC (5Q467) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-OSMR Antibody-APC (5Q467) is a APC-conjugated Rabbit antibody targeting OSMR. Anti-OSMR Antibody-APC (5Q467) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 5Q467 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human OSMR expression in HeLa cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human OSMR / IL-31RB (rh OSMR / IL-31RB; TMPY-01305; NP_003990.1; Met1-Met740) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| Research Background | Oncostatin-M specific receptor subunit beta also known as the oncostatin M receptor (OSMR) and Interleukin-31 receptor subunit beta (IL-31RB), is one of the receptor proteins for oncostatin M. OSMR is a member of the type I cytokine receptor family. IL-31RB/OSMR heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in IL-31RB/OSMR have been associated with familial primary localized cutaneous amyloidosis. Defects in IL-31RB/OSMR are the cause of amyloidosis primary localized cutaneous type 1 (PLCA1), also known as familial lichen amyloidosis of familial cutaneous lichen amyloidosis. PLCA1 is hereditary primary amyloidosis characterized by localized cutaneous amyloid deposition. This condition usually presents with itching (especially on the lower legs) and visible changes of skin hyperpigmentation and thickening (lichenification) that may be exacerbated by chronic scratching and rubbing. The amyloid deposits probably reflect a combination of degenerate keratin filaments, serum amyloid P component, and deposition of immunoglobulins. |
| Conjucates | APC |
| Others Formats | Unconjugated/PE |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human OSMR / IL-31RB protein (TMPY-01305) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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