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Anti-RBP4 Antibody-PE (2J141)
🥰Excellent
Catalog No. TMAY-00680P
Anti-RBP4 Antibody-PE (2J141) is a PE-conjugated Mouse antibody targeting RBP4. Anti-RBP4 Antibody-PE (2J141) can be used in FCM.
Anti-RBP4 Antibody-PE (2J141)
Anti-RBP4 Antibody-PE (2J141)
🥰Excellent
Catalog No. TMAY-00680P
Anti-RBP4 Antibody-PE (2J141) is a PE-conjugated Mouse antibody targeting RBP4. Anti-RBP4 Antibody-PE (2J141) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-RBP4 Antibody-PE (2J141) is a PE-conjugated Mouse antibody targeting RBP4. Anti-RBP4 Antibody-PE (2J141) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 2J141 |
| Reactivity | Human |
| Verified Activity | Profile of anti-RBP4 reactivity on HepG2 cells analyzed by flow cytometry. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and stained with PE conjugated Mouse anti-RBP4, The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RBP4 (rh RBP4; TMPY-00907; NP_006735.2; Met 1-Leu 201) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.1% sodium azide |
| Research Background | Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a β-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM). |
| Conjucates | PE |
| Others Formats | Unconjugated/FITC |
| Antibody Types Available | 3 |
| Immunogen | Recombinant Human RBP4 protein (TMPY-00907) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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