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Cemiplimab (Synonyms: SAR-439684, REGN-2810)
Catalog No. T76750 Copy Product Info
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Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody that inhibits the PD-1/PD-L1 pathway, serving as a checkpoint inhibitor. It is applicable in research on metastatic cancer and squamous cell skin cancer.
Cemiplimab
Copy Product Info🥰Excellent
Catalog No. T76750
Synonyms SAR-439684, REGN-2810
Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody that inhibits the PD-1/PD-L1 pathway, serving as a checkpoint inhibitor. It is applicable in research on metastatic cancer and squamous cell skin cancer.
Cemiplimab
Cas No. 1801342-60-8
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $163 | In Stock | In Stock | |
| 5 mg | $497 | - | In Stock | |
| 10 mg | $797 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 97.2% (SDS-PAGE); 95.2% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody that inhibits the PD-1/PD-L1 pathway, serving as a checkpoint inhibitor. It is applicable in research on metastatic cancer and squamous cell skin cancer. |
| In vivo | In a mouse model with MC38.Ova tumors, Cemiplimab (i.p., 10 mg/kg, five injections within 2 weeks) increased the proportion of effector T cells in tumors and dLNs, resulting in reduced tumor growth when combined with immunotherapy using REGN3767[2]. |
| Synonyms | SAR-439684, REGN-2810 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | PDCD1/PD-1/CD279 |
| Molecular Weight | 143.81 kDa |
| Cas No. | 1801342-60-8 |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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