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Cemiplimab (Synonyms: SAR-439684, REGN-2810)
Catalog No. T76750 Copy Product Info
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Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody that inhibits the PD-1/PD-L1 pathway, serving as a checkpoint inhibitor. It is applicable in research on metastatic cancer and squamous cell skin cancer.
Cemiplimab
Copy Product Info🥰Excellent
Catalog No. T76750
Synonyms SAR-439684, REGN-2810
Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody that inhibits the PD-1/PD-L1 pathway, serving as a checkpoint inhibitor. It is applicable in research on metastatic cancer and squamous cell skin cancer.
Cemiplimab
Cas No. 1801342-60-8
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $163 | In Stock | In Stock | |
| 5 mg | $497 | - | In Stock | |
| 10 mg | $797 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 97.2% (SDS-PAGE); 95.2% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Cemiplimab (Anti-Human PD-1) is a human monoclonal antibody that inhibits the PD-1/PD-L1 pathway, serving as a checkpoint inhibitor. It is applicable in research on metastatic cancer and squamous cell skin cancer. |
| In vivo | In a mouse model with MC38.Ova tumors, Cemiplimab (i.p., 10 mg/kg, five injections within 2 weeks) increased the proportion of effector T cells in tumors and dLNs, resulting in reduced tumor growth when combined with immunotherapy using REGN3767[2]. |
| Synonyms | SAR-439684, REGN-2810 |
| Reactivity | Human |
| Verified Activity | Immobilized Human PD-1 Protein (His) (TMPY-00897) at 1 μg/mL (100 μL/well) can bind Cemiplimab. The EC50 is 5.33 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | PDCD1/PD-1/CD279 |
| Molecular Weight | 143.81 kDa |
| Cas No. | 1801342-60-8 |
| Isotype | Human IgG4 kappa |
| Recommended Isotype Control |
| Storage | -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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