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m-PEG4-Hydrazide is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $970 | 4-6 weeks | |
25 mg | $1,370 | 4-6 weeks | |
50 mg | $1,850 | 4-6 weeks | |
100 mg | $2,500 | 4-6 weeks |
Description | m-PEG4-Hydrazide is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs (proteolysis-targeting chimeras) consist of two distinct ligands linked together: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. These compounds utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 250.29 |
Formula | C10H22N2O5 |
Cas No. | 1449390-68-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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