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Anti-Phospho-FOXO4 (Thr451) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO4 (Thr451). Anti-Phospho-FOXO4 (Thr451) Polyclonal Antibody can be used in WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $217 | 7-10 days | |
100 μL | $318 | 7-10 days |
Description | Anti-Phospho-FOXO4 (Thr451) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FOXO4 (Thr451). Anti-Phospho-FOXO4 (Thr451) Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
Reactivity | Human |
Application | |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Appearance | Liquid |
Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity. |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | Peptide sequence around phosphorylation site of Threonine 451 (L-G-T(p)-P-V) derived from Human FOXO4 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Actual: 65 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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