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Anti-PDIA6 Antibody (6G49)

(Synonyms: TXNDC7, Thioredoxin Domain-Containing Protein 7, Protein Disulfide-Isomerase A6, Protein Disulfide Isomerase P5, PDIA6, P5, ERP5, ER Protein 5, Endoplasmic Reticulum Protein 5) Copy Product Info
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Synonyms: TXNDC7, Thioredoxin Domain-Containing Protein 7, Protein Disulfide-Isomerase A6, Protein Disulfide Isomerase P5, PDIA6, P5, ERP5, ER Protein 5, Endoplasmic Reticulum Protein 5

Catalog No. TMAC-03134 Copy Product Info
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Anti-PDIA6 Antibody (6G49) is a Rabbit antibody targeting PDIA6. Anti-PDIA6 Antibody (6G49) can be used in FCM,ICC/IF,WB.

Anti-PDIA6 Antibody
(6G49)

Pack SizePriceUSA StockGlobal StockQuantity
50 µL$2987-10 days7-10 days
100 µL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PDIA6 Antibody (6G49) is a Rabbit antibody targeting PDIA6. Anti-PDIA6 Antibody (6G49) can be used in FCM,ICC/IF,WB.
SynonymsTXNDC7, Thioredoxin Domain-Containing Protein 7, Protein Disulfide-Isomerase A6, Protein Disulfide Isomerase P5, PDIA6, P5, ERP5, ER Protein 5, Endoplasmic Reticulum Protein 5
Ig Type
IgG
Clone
6G49
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of PDIA6 on different lysates using anti-PDIA6 antibody at 1/1,000 dilution. Positive control: Lane 1: HepG2, Lane 2: K562.
2. ICC staining PDIA6 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining PDIA6 in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining PDIA6 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Flow cytometric analysis of Hela cells with PDIA6 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
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Application
Recommended Dose
WB: 1:1000-2000; ICC/IF: 1:100-500; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundEndoplasmic reticulum proteins (ERps) are widely expressed proteins that localize to the ER and may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases or phospholipases. ERp5, also known as PDIA6 (protein disulfide isomerase family A, member 6) or TXNDC7 is a 440 amino acid protein that contains two thioredoxin domains and belongs to the protein disulfide isomerase family. Localized to the melanosome, as well as to the lumen of the endoplasmic reticulum, ERp5 functions to catalyze the rearrangement of disulfide bonds in a variety of different proteins. Via its catalytic activity, ERp5 is able to reduce the disulfide bond that binds MICA to tumor cells, thereby releasing MICA and reducing the rate of tumor expansion. Multiple isoforms of ERp5 exist due to alternative splicing events.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 48 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: Anti-PDIA6 Antibody (6G49) molecular weight