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Anti-PDIA6 Antibody (6G49)
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Catalog No. TMAC-03134
Alias TXNDC7, Thioredoxin Domain-Containing Protein 7, Protein Disulfide-Isomerase A6, Protein Disulfide Isomerase P5, PDIA6, P5, ERP5, ER Protein 5, Endoplasmic Reticulum Protein 5
Anti-PDIA6 Antibody (6G49) is a Rabbit antibody targeting PDIA6. Anti-PDIA6 Antibody (6G49) can be used in WB,ICC/IF,FCM.
Anti-PDIA6 Antibody (6G49)
Anti-PDIA6 Antibody (6G49)
😃Good
Catalog No. TMAC-03134Alias TXNDC7, Thioredoxin Domain-Containing Protein 7, Protein Disulfide-Isomerase A6, Protein Disulfide Isomerase P5, PDIA6, P5, ERP5, ER Protein 5, Endoplasmic Reticulum Protein 5
Anti-PDIA6 Antibody (6G49) is a Rabbit antibody targeting PDIA6. Anti-PDIA6 Antibody (6G49) can be used in WB,ICC/IF,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-PDIA6 Antibody (6G49) is a Rabbit antibody targeting PDIA6. Anti-PDIA6 Antibody (6G49) can be used in WB,ICC/IF,FCM. |
| Synonyms | TXNDC7, Thioredoxin Domain-Containing Protein 7, Protein Disulfide-Isomerase A6, Protein Disulfide Isomerase P5, PDIA6, P5, ERP5, ER Protein 5, Endoplasmic Reticulum Protein 5 |
| Ig Type | IgG |
| Clone | 6G49 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of PDIA6 on different lysates using anti-PDIA6 antibody at 1/1,000 dilution. Positive control: Lane 1: HepG2, Lane 2: K562. 2. ICC staining PDIA6 in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining PDIA6 in HepG2 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining PDIA6 in NIH/3T3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of Hela cells with PDIA6 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:100-500; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Endoplasmic reticulum proteins (ERps) are widely expressed proteins that localize to the ER and may act as proteases, protein disulfide isomerases, thiol-disulfide oxidases or phospholipases. ERp5, also known as PDIA6 (protein disulfide isomerase family A, member 6) or TXNDC7 is a 440 amino acid protein that contains two thioredoxin domains and belongs to the protein disulfide isomerase family. Localized to the melanosome, as well as to the lumen of the endoplasmic reticulum, ERp5 functions to catalyze the rearrangement of disulfide bonds in a variety of different proteins. Via its catalytic activity, ERp5 is able to reduce the disulfide bond that binds MICA to tumor cells, thereby releasing MICA and reducing the rate of tumor expansion. Multiple isoforms of ERp5 exist due to alternative splicing events. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 48 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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