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JAK-IN-14 (compound 16) is a specific JAK1 inhibitor with IC50<5 μM. It prevents JAK1 phosphorylation by binding to the active site of JAK1, and is more than 8-fold selective for JAK1 over JAK2/JAK3, and can be used in immune, inflammation and cancer research.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $81 | In Stock | |
5 mg | $198 | In Stock | |
10 mg | $312 | In Stock | |
25 mg | $648 | In Stock | |
50 mg | $987 | In Stock | |
100 mg | $1,570 | In Stock | |
200 mg | $2,090 | In Stock | |
1 mL x 10 mM (in DMSO) | $219 | In Stock |
Description | JAK-IN-14 (compound 16) is a specific JAK1 inhibitor with IC50<5 μM. It prevents JAK1 phosphorylation by binding to the active site of JAK1, and is more than 8-fold selective for JAK1 over JAK2/JAK3, and can be used in immune, inflammation and cancer research. |
Molecular Weight | 334.35 |
Formula | C19H15FN4O |
Cas No. | 1973485-06-1 |
Smiles | N#CCC=1C=CC(=C(F)C1)C2=CC=CC3=NC(=CN32)NC(=O)C4CC4 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
Solubility Information | DMSO: 5 mg/mL (14.95 mM), Sonication and heating are recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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