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ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P47895.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 μg | $108 | 7-10 days | 7-10 days | |
| 10 μg | $178 | 7-10 days | 7-10 days | |
| 20 μg | $296 | 7-10 days | 7-10 days | |
| 50 μg | $696 | 7-10 days | 7-10 days |
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P47895. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-6His |
| Accession Number | P47895 |
| Synonyms | RALDH3,MCOP8,ALDH6,ALDH1A6,aldehyde dehydrogenase 1 family, member A3 |
| Construction | Met1-Pro512 |
| Protein Purity | > 95% as determined by SDS-PAGE. |
| Molecular Weight | 57.5 kDa (Predicted); 55-60 kDa (Reducing conditions) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 20% Glycerol, pH 7.5. |
| Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Solutions are shipping with dry ice. |
| Research Background | Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers. |
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