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ALDH1A3 Protein, Human, Recombinant (His)

Catalog No. TMPY-01899
Synonyms: ALDH6, aldehyde dehydrogenase 1 family, member A3, ALDH1A6, RALDH3, MCOP8

ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95.

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ALDH1A3 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
50 μg 5 days $ 600.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description ALDH1A3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 57 kDa and the accession number is A0A024RC95.
Species Human
Expression System E. coli
Tag His
Accession Number A0A024RC95
Synonyms ALDH6, aldehyde dehydrogenase 1 family, member A3, ALDH1A6, RALDH3, MCOP8
Construction A DNA sequence encoding the human ALDH1A3 (NP_000684.2) (Ala 2-Pro 512) was expressed, with a polyhistide tag at the N-terminus.
Protein Purity > 96 % as determined by SDS-PAGE
Molecular Weight 57 kDa (predicted)
Endotoxin Please contact us for more information.
Formulation Supplied as sterile PBS 7.4 10% glycerol 0. 2% TWEEN20Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

Solution. It is shipped out with blue ice.

Research Background Aldehyde dehydrogenase 1 family, member A3 (ALDH1A3), also known as Retinaldehyde dehydrogenase 3 (RALDH3), which belongs to the aldehyde dehydrogenase family. ALDH1A3 is a novel Cancer stem cell (CSC) marker with potential clinical prognostic applicability, and demonstrates a clear correlation between CSC prevalence and the development of metastatic breast cancer. The retinoic acid (RA) biosynthesis enzyme aldehyde dehydrogenase 1A3 (ALDH1A3) is a putative androgen-responsive gene in human prostate cancer epithelial (LNCaP) cells. The RA biosynthesis enzyme ALDH1A3 is androgen responsive and (ii) DHT up-regulation of ALDH1A3 can increase the oxidation of retinal to RA and indirectly affect RA bioactivity and metabolism.

References and Literature

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Keywords

ALDH1A3 Protein, Human, Recombinant (His) ALDH 6 ALDH6 ALDH-6 MCOP 8 aldehyde dehydrogenase 1 family, member A3 RALDH-3 ALDH1A6 RALDH3 MCOP8 RALDH 3 MCOP-8 recombinant recombinant-proteins proteins protein

 

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