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Metabolism

Acetyl-CoA Carboxylase

Amino Acids and Derivatives

Angiotensin-converting Enzyme (ACE)

Endogenous Metabolite

Glutathione Peroxidase

(80)

Glyoxalase

(17)

HIF/HIF Prolyl-Hydroxylase

Indoleamine 2,3-Dioxygenase (IDO)

(100)

Isocitrate Dehydrogenase (IDH)

Mitochondrial Metabolism

(217)

N-Acetylglucosaminyltransferase

Procollagen C Proteinase

(1)

Prolyl Endopeptidase (PREP)

Reactive Oxygen Species

Serine/threonin kinase

(91)

Stearoyl-CoA Desaturase (SCD)

Vitamin

Vitamins are organic molecules (or a set of closely related molecules called vitamers) that are essential to an organism in small quantities for proper metabolic function. Essential nutrients cannot be synthesized in the organism in sufficient quantities for survival, and therefore must be obtained through the diet.

Filter HomeSignaling PathwaysMetabolismVitamin

Paricalcitol

TQ0200131918-61-1

Paricalcitol is a vitamin D receptor agonist. It is used for the prevention and treatment of secondary hyperparathyroidism associated with chronic renal failure.

$147

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Calcitriol

T631632222-06-3

Calcitriol (1,25-Dihydroxyvitamin D3) is a metabolite of vitamin D and a vitamin D receptor (VDR) agonist (IC50=0.4 nM). Calcitriol increases intestinal absorption of calcium and phosphorus, and increases bone resorption with parathyroid hormone.

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Cited

Biotin

T111658-85-5

Biotin (Vitamin H) is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.

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Calcipotriol

T14856112965-21-6

Calcipotriol (MC 903) is a synthetic vitamin D3 analogue with high affinity for the vitamin D receptor.

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Vitamin D3

T113567-97-0

Vitamin D3 (Cholecalciferol) is a naturally occurring form of vitamin D that, after metabolic activation, can induce cell differentiation and cancer cell proliferation. It can also be used to establish kidney stone models.

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24, 25-Dihydroxy VD2

T1910758050-55-8

24, 25-Dihydroxy VD2 (24,25-Dihydroxy vitamin D2) is a metabolite of vitamin D2, which is the isomer of vitamin D present in the body as 25-hydroxyvitamin D. PF-04957325 is used in the study of autoimmune encephalomyelitis.

$599

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Inecalcitol

T24166163217-09-2

Inecalcitol is a unique vitamin D3 analog that induces apoptosis and has anticancer activity. It is an orally active vitamin D receptor agonist with a Kd of 0.53 nM.

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Calcipotriol monohydrate

TQ0244147657-22-5

Calcipotriol monohydrate is an analog of Vitamin D3 with a high affinity for the vitamin D receptor. Calcipotriol monohydrate can be used for studies about psoriasis.

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Ercalcidiol

T1524221343-40-8

Ercalcidiol [is a metabolite of vitamin D2] and is useful for monitoring vitamin D therapy.

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Maxacalcitol

T16015103909-75-7

Maxacalcitol (22-Oxacalcitriol) is a ligand of VDR-like receptors and a non-serum calcium vitamin D3 analogue. Maxacalcitol inhibits parathyroid hormone (PTH) mRNA expression in vitro and in vivo.

4-6 weeks

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Vitamin D2

T108650-14-6

Ergocalciferol (Vitamin D2 (Calciferol)) is a derivative of ergosterol formed by ultraviolet rays breaking of the C9-C10 bond with a strong inhibitory effect against bladder tumor promotion by sodium saccharin, and it induces cell differentiation in leukemia cells. Vitamin D2 is an inhibitor of DNA Polymerase.

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MeTC7

T701511817841-22-7

MeTC7 is a vitamin D receptor (VDR) antagonist with antitumor activity that inhibits PD-L1 and may inhibit the growth of xenografts and transgenic tumors in vivo.

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Ercalcitriol

TQ021660133-18-8

Ercalcitriol (1α,25-Dihydroxy Vitamin D2) is an active metabolite of vitamin D2 that strengthens immunity by regulating cathelicidin antimicrobial peptide (CAMP) and defensin β-4 (DEFB4) genes in normal and transformed cells, combating pathogenic infections.

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Retinyl acetate

T0685127-47-9

Retinyl acetate (Vitamin A acetate) is a group of unsaturated nutritional hydrocarbons, that contains retinal, retinol, retinoic acid, and several provitamins A carotenoids, among which beta-carotene is the most important.

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5,6-trans-Vitamin D3

T3550122350-41-0In house

5,6-trans-Vitamin D3(5,6-trans-Cholecalciferol) is an isoform of Vitamin D3, which is converted from Vitamin D3 on the skin surface after light exposure.

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Tacalcitol monohydrate

T1391193129-94-3

Tacalcitol monohydrate(Curatoderm monohydrate), a vitamin D3 analog that promotes bone development by regulating calcium ions, can be used to study psoriasis.

$113

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Calcifediol monohydrate

T6430L63283-36-3

Calcifediol monohydrate (25-hydroxy Vitamin D3 monohydrate), the primary circulating metabolite of Vitamin D3, serves as a potent VDR inhibitor.

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Alfacalcidol

T637441294-56-8

Alfacalcidol (Etalpha) (1-hydroxycholecalciferol; Alpha D3; 1.alpha.-Hydroxyvitamin D3) is a non-selective VDR activator medication.

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Coumetarol

T108674366-18-1

Coumetarol (Dicumoxane) is a vitamin K antagonist and an oral anticoagulant that can be used to study arterial thrombotic occlusion.

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Acenocoumarol

TQ0197152-72-7

Acenocoumarol is a Vitamin K antagonist and used as an anticoagulant.

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Dihydrotachysterol

T2141767-96-9

Dihydrotachysterol (HSDB 3314) is a vitamin D analog.Dihydrotachysterol has been used to study hypocalcemic hypoparathyroidism after surgical removal of the parathyroid glands and growth impairment in children with chronic renal insufficiency.

$149

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Doxercalciferol

T611254573-75-0

Doxercalciferol (TSA 840) is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease.

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DL-Panthenol

T139016485-10-2

DL-Panthenol (DL-Pantothenyl alcohol) is the alcohol analog of pantothenic acid (vitamin B5) and is thus a provitamin of B5. In organisms, it is quickly oxidized to pantothenate.

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25,26-Dihydroxyvitamin D3

T1349029261-12-9

25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a vitamin D3 metabolite and a precursor compound for the synthesis of 25-hydroxyvitamin D.

$2,318

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