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Phytanic acid
Catalog No. T73757 Copy Product Info
Purity: 99.77%
🥰Excellent
Pristanic acid is an endogenous branched fatty acid produced by α -oxidation of phytanic acid, which is further metabolized by β -oxidation in peroxisome. As a metabolite of fatty acids, Pristanic acid can be used as a ligand to activate PPARα, thus regulating the expression of genes related to lipid metabolism and energy homeostasis. Its metabolic abnormalities are related to a variety of peroxisome-related diseases, including Zellweger syndrome, α -methyl acyl-coenzyme A racemase deficiency, and infantile Refsum disease.
Phytanic acid
Copy Product Info🥰Excellent
Catalog No. T73757
Pristanic acid is an endogenous branched fatty acid produced by α -oxidation of phytanic acid, which is further metabolized by β -oxidation in peroxisome. As a metabolite of fatty acids, Pristanic acid can be used as a ligand to activate PPARα, thus regulating the expression of genes related to lipid metabolism and energy homeostasis. Its metabolic abnormalities are related to a variety of peroxisome-related diseases, including Zellweger syndrome, α -methyl acyl-coenzyme A racemase deficiency, and infantile Refsum disease.
Cas No. 14721-66-5
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $138 | - | In Stock | |
| 5 mg | $337 | - | In Stock | |
| 10 mg | $638 | - | In Stock | |
| 25 mg | $1,080 | - | In Stock | |
| 50 mg | $1,430 | - | In Stock | |
| 100 mg | $1,920 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.77%
Appearance:Oil
Color:Yellow
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Pristanic acid is an endogenous branched fatty acid produced by α -oxidation of phytanic acid, which is further metabolized by β -oxidation in peroxisome. As a metabolite of fatty acids, Pristanic acid can be used as a ligand to activate PPARα, thus regulating the expression of genes related to lipid metabolism and energy homeostasis. Its metabolic abnormalities are related to a variety of peroxisome-related diseases, including Zellweger syndrome, α -methyl acyl-coenzyme A racemase deficiency, and infantile Refsum disease. |
| In vitro | In cell proliferation assays using multiple cancer cell lines, Phytanic acid acted as an endogenous toxic metabolite and induced significant apoptosis and cell cycle arrest [1]. |
| In vivo | In tumor-bearing mouse models, systemic administration of Phytanic acid resulted in a decrease in tumor burden [1]. |
| Molecular Weight | 312.53 |
| Formula | C20H40O2 |
| Cas No. | 14721-66-5 |
| Smiles | O=C(O)CC(C)CCCC(C)CCCC(C)CCCC(C)C |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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