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Anti-Phospho-PIN1 (Ser16) Polyclonal Antibody

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Catalog No. TMAC-03300

Anti-Phospho-PIN1 (Ser16) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PIN1 (Ser16). Anti-Phospho-PIN1 (Ser16) Polyclonal Antibody can be used in WB.

Anti-Phospho-PIN1 (Ser16) Polyclonal Antibody

Anti-Phospho-PIN1 (Ser16) Polyclonal Antibody

😃Good
Catalog No. TMAC-03300
Anti-Phospho-PIN1 (Ser16) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PIN1 (Ser16). Anti-Phospho-PIN1 (Ser16) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3187-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-PIN1 (Ser16) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PIN1 (Ser16). Anti-Phospho-PIN1 (Ser16) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundEssential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine16(R-M-S(p)-R-S) derived from Human Pin1
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 18 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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