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Resistin Protein, Human, Recombinant (His)

Catalog No. TMPJ-00014
Synonyms: Resistin, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, RSTN, Cysteine-rich secreted protein A12-α-like 2, RETN, FIZZ3, HXCP1, C/EBP-ε-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein FIZZ3, Adipose tissue-specific secretory factor, Cysteine-rich secreted protein A12-alpha-like 2

Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM). Resistin has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease, resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Resistin Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 116.00
50 μg 5 days $ 352.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM). Resistin has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease, resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.
Species Human
Expression System E. coli
Tag C-6His
Accession Number Q9HD89
Synonyms Resistin, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, RSTN, Cysteine-rich secreted protein A12-α-like 2, RETN, FIZZ3, HXCP1, C/EBP-ε-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein FIZZ3, Adipose tissue-specific secretory factor, Cysteine-rich secreted protein A12-alpha-like 2
Amino Acid Lys19-Pro108
Construction Recombinant Human Adipose Tissue-specific Secretory Factor is produced by our E.coli expression system and the target gene encoding Lys19-Pro108 is expressed with a 6His tag at the C-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 10—14 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM HAc, pH 3.0.
Reconstitution Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. 
Stability & Storage

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below.
Research Background Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. The length of the resistin pre-peptide in human is 108 amino acid residues and in the mouse and rat it is 114 aa; the molecular weight is ~12.5 kDa. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus (T2DM). Resistin has been shown to cause "high levels of 'bad' cholesterol (low-density lipoprotein or LDL), increasing the risk of heart disease, resistin increases the production of LDL in human liver cells and also degrades LDL receptors in the liver. Potentially links obesity to diabetes.

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Keywords

Resistin Protein, Human, Recombinant (His) Resistin C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein HXCP 1 FIZZ-3 RSTN Cysteine-rich secreted protein A12-α-like 2 HXCP-1 RETN FIZZ3 HXCP1 FIZZ 3 C/EBP-ε-regulated myeloid-specific secreted cysteine-rich protein Cysteine-rich secreted protein A12-a-like 2 Cysteine-rich secreted protein FIZZ3 Adipose tissue-specific secretory factor Cysteine-rich secreted protein A12-alpha-like 2 recombinant recombinant-proteins proteins protein

 

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