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ε-NAADP+ is a fluorescent derivative of NAADP, known for inducing calcium mobilization. It effectively induces calcium release in sea urchin egg homogenates with an EC50 of 5 µM. The compound exhibits excitation and emission maxima at 275 nm and 410 nm, respectively. Notably, its emission intensity increases three-fold when dissolved in DMSO.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | Inquiry | 3-6 months | 3-6 months | |
| 50 mg | Inquiry | 3-6 months | 3-6 months | |
| 100 mg | Inquiry | 3-6 months | 3-6 months |
| Description | ε-NAADP+ is a fluorescent derivative of NAADP, known for inducing calcium mobilization. It effectively induces calcium release in sea urchin egg homogenates with an EC50 of 5 µM. The compound exhibits excitation and emission maxima at 275 nm and 410 nm, respectively. Notably, its emission intensity increases three-fold when dissolved in DMSO. |
| Synonyms | β-Nicotinic Acid-1, Nicotinic Acid adenine dinucleotide phosphate, N6-Ethenoadenine dinucleotide phosphate, Etheno-NAADP |
| Molecular Weight | 857.40 |
| Formula | C23H24N6O18P3.4Na |
| Smiles | O[C@@H]1[C@@H](COP([O-])(OP(OC[C@@H]2[C@@H](O)[C@@H](O)[C@H]([N+]3=CC=CC(C(O)=O)=C3)O2)([O-])=O)=O)O[C@@H](N4C=NC5=C4N=CN6C5=NC=C6)[C@@H]1OP([O-])([O-])=O.[Na+].[Na+].[Na+].[Na+] |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: Soluble |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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