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Anti-Eotaxin/CCL11 Polyclonal Antibody

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Catalog No. TMAB-00619
Alias Small-Inducible Cytokine A11, SCYA11, Eotaxin, Eosinophil Chemotactic Protein, CCL11, C-C Motif Chemokine 11

Anti-Eotaxin/CCL11 Polyclonal Antibody is a Rabbit antibody targeting Eotaxin/CCL11. Anti-Eotaxin/CCL11 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.

Anti-Eotaxin/CCL11 Polyclonal Antibody

Anti-Eotaxin/CCL11 Polyclonal Antibody

😃Good
Catalog No. TMAB-00619Alias Small-Inducible Cytokine A11, SCYA11, Eotaxin, Eosinophil Chemotactic Protein, CCL11, C-C Motif Chemokine 11
Anti-Eotaxin/CCL11 Polyclonal Antibody is a Rabbit antibody targeting Eotaxin/CCL11. Anti-Eotaxin/CCL11 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Eotaxin/CCL11 Polyclonal Antibody is a Rabbit antibody targeting Eotaxin/CCL11. Anti-Eotaxin/CCL11 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
SynonymsSmall-Inducible Cytokine A11, SCYA11, Eotaxin, Eosinophil Chemotactic Protein, CCL11, C-C Motif Chemokine 11
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat)
Verified Activity
1. Images kindly provided by Dr. Denny Cottle from the publication, Fetal inhibition of inflammation improves disease phenotypes in Harlequin Ichthyosis.Formalin-fixed and paraffin embedded mouse skin probed with Rabbit Anti-CCL11/Eotaxin 1 Polyclonal Antibody (TMAB-00619) at 1:100 for two hours at room temperature (green channel).
2. Paraformaldehyde-fixed, paraffin embedded (mouse stomach); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (CCL11) Polyclonal Antibody, Unconjugated (TMAB-00619) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
verifiedActivityverifiedActivity
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1 mg/mL
Research BackgroundThis gene is one of several Cys-Cys (CC) cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil specific chemokine assumed to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Eotaxin 1
Antigen Species
Human
Gene Name
CCL11
Gene ID
Protein Name
Eotaxin
Uniprot ID
Function
In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3.
Chemical Properties
Molecular WeightTheoretical: 8 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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