Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotactic effects by binding to the chemokine receptor CCR10. Predominantly expressed in the skin, CCL27 is associated with T cell-mediated inflammation of the skin. Human and Mouse CCL27 share 84% sequence identity in the mature form.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 143.00 | |
50 μg | 5 days | $ 434.00 | |
500 μg | 5 days | $ 1,530.00 | |
1 mg | 5 days | $ 2,180.00 |
Description | Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotactic effects by binding to the chemokine receptor CCR10. Predominantly expressed in the skin, CCL27 is associated with T cell-mediated inflammation of the skin. Human and Mouse CCL27 share 84% sequence identity in the mature form. |
Species | Human |
Expression System | E. coli |
Tag | None |
Accession Number | Q9Y4X3 |
Synonyms | ILC, Small-Inducible Cytokine A27, IL-11 R-Alpha-Locus Chemokine, CCL27, C-C Motif Chemokine 27, IL-11 R-α-Locus Chemokine, Skinkine, CC Chemokine ILC, Eskine, Cutaneous T-Cell-Attracting Chemokine, SCYA27, CTACK |
Amino Acid | Phe25-Gly112 |
Construction | Recombinant Human C-C Motif Chemokine 27 is produced by our E.coli expression system and the target gene encoding Phe25-Gly112 is expressed. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 6-12 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 100mM Nacl, 6% Trehalose, 4% Mannitol, 0.05% Tween80, pH7.0. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotactic effects by binding to the chemokine receptor CCR10. Predominantly expressed in the skin, CCL27 is associated with T cell-mediated inflammation of the skin. Human and Mouse CCL27 share 84% sequence identity in the mature form. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CCL27 Protein, Human, Recombinant IL-11 R-a-Locus Chemokine CCL 27 ILC Small-Inducible Cytokine A27 SCYA-27 CCL-27 IL-11 R-Alpha-Locus Chemokine CCL27 C-C Motif Chemokine 27 IL-11 R-α-Locus Chemokine Skinkine CC Chemokine ILC Eskine Cutaneous T-Cell-Attracting Chemokine SCYA 27 SCYA27 CTACK recombinant recombinant-proteins proteins protein