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Anti-DARPP-32 Antibody (1B13)

(Synonyms: Protein phosphatase 1 regulatory subunit 1B, Protein phosphatase 1 regulatory inhibitor subunit 1B, Protein phosphatase 1 regulatory (inhibitor) subunit 1B, PPR1B_HUMAN, PPP1R1B, Neuronal phosphoprotein DARPP 32, IPPD, FLJ20940, Dopamine- and cAMP-regulated neuronal phosphoprotein, Dopamine and cAMP regulated phosphoprotein DARPP32, Dopamine and cAMP regulated phosphoprotein DARPP 32, Dopamine and cAMP regulated phosphoprotein, Dopamine and cAMP regulated neuronal phosphoprotein 32, Dopamine and cAMP regulated neuronal phosphoprotein, DARPP32, DARPP 32) Copy Product Info
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Synonyms: Protein phosphatase 1 regulatory subunit 1B, Protein phosphatase 1 regulatory inhibitor subunit 1B, Protein phosphatase 1 regulatory (inhibitor) subunit 1B, PPR1B_HUMAN, PPP1R1B, Neuronal phosphoprotein DARPP 32, IPPD, FLJ20940, Dopamine- and cAMP-regulated neuronal phosphoprotein, Dopamine and cAMP regulated phosphoprotein DARPP32, Dopamine and cAMP regulated phosphoprotein DARPP 32, Dopamine and cAMP regulated phosphoprotein, Dopamine and cAMP regulated neuronal phosphoprotein 32, Dopamine and cAMP regulated neuronal phosphoprotein, DARPP32, DARPP 32

Catalog No. TMAC-01115 Copy Product Info
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Anti-DARPP-32 Antibody (1B13) is a Rabbit antibody targeting DARPP-32. Anti-DARPP-32 Antibody (1B13) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-DARPP-32 Antibody
(1B13)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-DARPP-32 Antibody (1B13) is a Rabbit antibody targeting DARPP-32. Anti-DARPP-32 Antibody (1B13) can be used in FCM,ICC/IF,IHC,IP,WB.
SynonymsProtein phosphatase 1 regulatory subunit 1B, Protein phosphatase 1 regulatory inhibitor subunit 1B, Protein phosphatase 1 regulatory (inhibitor) subunit 1B, PPR1B_HUMAN, PPP1R1B, Neuronal phosphoprotein DARPP 32, IPPD, FLJ20940, Dopamine- and cAMP-regulated neuronal phosphoprotein, Dopamine and cAMP regulated phosphoprotein DARPP32, Dopamine and cAMP regulated phosphoprotein DARPP 32, Dopamine and cAMP regulated phosphoprotein, Dopamine and cAMP regulated neuronal phosphoprotein 32, Dopamine and cAMP regulated neuronal phosphoprotein, DARPP32, DARPP 32
Ig Type
IgG
Clone
1B13
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundDopaminergic signaling pathways, which are essential for multiple brain functions, are abnormal in several neurological disorders, such as schizophrenia, Parkinson's disease and drug abuse. DARPP-32 (for dopamine and adenosine 3',5'-monophosphate-regulated phosphoprotein) is abundant in neurons that receive dopaminergic input. Activation of PKA and the consequent phosphorylation of DARPP-32 on threonine occurs in response to dopamine acting upon D1-like receptors. Dopamine interaction with D2-like receptors results in the inhibition of PKA activation, the activation of protein phosphatase 2B and the consequent dephosphorylation of DARPP-32. Neurotransmitters other than dopamine may also be able to stimulate the phosphorylation or dephosphorylation of DARPP-32. Phosphorylated DARPP-32 is a potent inhibitor of PP-1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 32 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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