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Anti-Phospho-HER3/ERBB3 (Tyr1328) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HER3/ERBB3 (Tyr1328). Anti-Phospho-HER3/ERBB3 (Tyr1328) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $218 | 7-10 days | |
100 μL | $317 | 7-10 days |
Description | Anti-Phospho-HER3/ERBB3 (Tyr1328) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HER3/ERBB3 (Tyr1328). Anti-Phospho-HER3/ERBB3 (Tyr1328) Polyclonal Antibody can be used in IHC-P,IF(paraffin section),ELISA. |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Application | |
Recommended Dose | IHC-P: 1:100-300; ELISA: 1:5000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Construction | Polyclonal Antibody |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Appearance | Liquid |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Research Background | erb-b2 receptor tyrosine kinase 3(ERBB3) Homo sapiens This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the m |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human HER3 around the phosphorylation site of Tyr1328. AA range:1293-1342 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 148 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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