Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Minesapride, a novel 5-hydroxytryptamine 4 (5-HT4) receptor partial agonist, is a potential gastrointestinal prokinetic agent for the treatment of irritable bowel syndrome with constipation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 430.00 | |
10 mg | In stock | $ 636.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,360.00 | |
100 mg | In stock | $ 1,830.00 | |
500 mg | In stock | $ 3,680.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 497.00 |
Description | Minesapride, a novel 5-hydroxytryptamine 4 (5-HT4) receptor partial agonist, is a potential gastrointestinal prokinetic agent for the treatment of irritable bowel syndrome with constipation. |
In vivo | Minesapride (1, 4, 12, or 40 mg; once daily; 4 weeks) improved in Minesapride 40 mg group abdominal symptoms score at week 4. In a phase 2 trial of patients with IBS-C in Japan, minesapride increased stool frequency (measured by CSBMs), reduced abdominal and overall IBS-C symptoms, and was well tolerated.[1] |
Molecular Weight | 454.95 |
Formula | C21H31ClN4O5 |
CAS No. | 1184662-54-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (66.15 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Minesapride 1184662-54-1 GPCR/G Protein Neuroscience 5-HT Receptor (S)4amino5chloroN((4((1(2hydroxyacetyl)piperidin4yl)methyl)morpholin2yl)methyl)2methoxybenzamide inhibitor inhibit