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Apararenone

Name: Apararenone
Brand: TargetMol
SKU: T14301
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14301Cas No. 945966-46-1

Alias MT-3995

Apararenone (MT-3995) is a mineralocorticoid receptor antagonist indicated for the treatment of non-alcoholic steatohepatitis and diabetic nephropathy.

Apararenone

🥰Excellent

Purity: 99.79%

Catalog No. T14301Alias MT-3995Cas No. 945966-46-1

Apararenone (MT-3995) is a mineralocorticoid receptor antagonist indicated for the treatment of non-alcoholic steatohepatitis and diabetic nephropathy.

Pack Size	Price	Availability
2 mg	$35	In Stock
5 mg	$56	In Stock
10 mg	$84	In Stock
25 mg	$131	In Stock
50 mg	$189	In Stock
100 mg	$276	In Stock
1 mL x 10 mM (in DMSO)	$62	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.79%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Apararenone (MT-3995) is a mineralocorticoid receptor antagonist indicated for the treatment of non-alcoholic steatohepatitis and diabetic nephropathy.
Synonyms	MT-3995

Chemical Properties

Molecular Weight	364.39
Formula	C₁₇H₁₇FN₂O₄S
Cas No.	945966-46-1
Smiles	CC1(C)Oc2cc(NS(C)(=O)=O)ccc2N(C1=O)c1ccc(F)cc1
Relative Density.	1.389 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (343.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7443 mL	13.7216 mL	27.4431 mL	137.2156 mL
5 mM	0.5489 mL	2.7443 mL	5.4886 mL	27.4431 mL
10 mM	0.2744 mL	1.3722 mL	2.7443 mL	13.7216 mL
20 mM	0.1372 mL	0.6861 mL	1.3722 mL	6.8608 mL
50 mM	0.0549 mL	0.2744 mL	0.5489 mL	2.7443 mL
100 mM	0.0274 mL	0.1372 mL	0.2744 mL	1.3722 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc