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Anti-MYH11 Antibody (1K373)

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Catalog No. TMAY-00191
Alias VSCM2, SMMS-1, SMMHC, SMHC, KIAA0866, FAA4, AAT4

Anti-MYH11 Antibody (1K373) is a Rabbit antibody targeting MYH11. Anti-MYH11 Antibody (1K373) can be used in IHC-P.

Anti-MYH11 Antibody (1K373)

Anti-MYH11 Antibody (1K373)

😃Good
Catalog No. TMAY-00191Alias VSCM2, SMMS-1, SMMHC, SMHC, KIAA0866, FAA4, AAT4
Anti-MYH11 Antibody (1K373) is a Rabbit antibody targeting MYH11. Anti-MYH11 Antibody (1K373) can be used in IHC-P.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-MYH11 Antibody (1K373) is a Rabbit antibody targeting MYH11. Anti-MYH11 Antibody (1K373) can be used in IHC-P.
AliasVSCM2, SMMS-1, SMMHC, SMHC, KIAA0866, FAA4, AAT4
Ig Type
Monoclonal Rabbit IgG
Clone
1K373
Reactivity
Human
Verified Activity
1. Immunochemical staining of human MYH11 in human prostate with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).

2. Immunochemical staining of human MYH11 in human smooth muscle with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:100-1:500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human MYH11. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundThe MYH11 gene may be related to cell migration and adhesion, intracellular transport, and signal transduction. MYH11 functions as a contractile protein, converting chemical energy into mechanical energy through adenosine triphosphate hydrolysis.MYH11 (also known as SMMHC) encodes the smooth-muscle myosin heavy chain, which has a key role in smooth muscle contraction. Inversion at the MYH11 locus is one of the most frequent chromosomal aberrations found in acute myeloid leukemia. Mutations in myosin heavy chain (MYH11) cause autosomal dominant inheritance of thoracic aortic aneurysms and dissections. At the same time, rare, nonsynonymous variants in MYH11 that are predicted to disrupt protein function but do not cause inherited aortic disease are common in the general population. The human smooth muscle myosin heavy chain locus (MYH11) was mapped by fluorescence in situ hybridization to the middle of the p arm of chromosome 16 using a genomic cosmid clone containing coding sequences of the gene as probe.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide corresponding to the center region of the Human MYH11
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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