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Anti-MYH11 Antibody (1K373) is a Rabbit antibody targeting MYH11. Anti-MYH11 Antibody (1K373) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $268 | 7-10 days |
Description | Anti-MYH11 Antibody (1K373) is a Rabbit antibody targeting MYH11. Anti-MYH11 Antibody (1K373) can be used in IHC-P. |
Alias | VSCM2, SMMS-1, SMMHC, SMHC, KIAA0866, FAA4, AAT4 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1K373 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human MYH11 in human prostate with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human MYH11 in human smooth muscle with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human MYH11. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | The MYH11 gene may be related to cell migration and adhesion, intracellular transport, and signal transduction. MYH11 functions as a contractile protein, converting chemical energy into mechanical energy through adenosine triphosphate hydrolysis.MYH11 (also known as SMMHC) encodes the smooth-muscle myosin heavy chain, which has a key role in smooth muscle contraction. Inversion at the MYH11 locus is one of the most frequent chromosomal aberrations found in acute myeloid leukemia. Mutations in myosin heavy chain (MYH11) cause autosomal dominant inheritance of thoracic aortic aneurysms and dissections. At the same time, rare, nonsynonymous variants in MYH11 that are predicted to disrupt protein function but do not cause inherited aortic disease are common in the general population. The human smooth muscle myosin heavy chain locus (MYH11) was mapped by fluorescence in situ hybridization to the middle of the p arm of chromosome 16 using a genomic cosmid clone containing coding sequences of the gene as probe. |
Conjucates | Unconjugated |
Immunogen | A synthetic peptide corresponding to the center region of the Human MYH11 |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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