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UBE2A Protein, Human, Recombinant (GST, His)

Catalog No. TMPJ-00985
Synonyms: RAD6A, HR6A, Ubiquitin-Protein Ligase A, UBE2A, hHR6A, Ubiquitin Carrier Protein A, Ubiquitin-Conjugating Enzyme E2 A, RAD6 Homolog A

Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBE2A is required for postreplication repair of UV-damaged DNA. UBE2A Interacts with RAD18 and WAC.

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UBE2A Protein, Human, Recombinant (GST, His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 35.00
50 μg 5 days $ 91.00
500 μg 5 days $ 781.00
1 mg 5 days $ 1,120.00
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Biological Description
Technical Params
Product Properties
Description Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBE2A is required for postreplication repair of UV-damaged DNA. UBE2A Interacts with RAD18 and WAC.
Species Human
Expression System E. coli
Tag N-GST,6His
Accession Number P49459
Synonyms RAD6A, HR6A, Ubiquitin-Protein Ligase A, UBE2A, hHR6A, Ubiquitin Carrier Protein A, Ubiquitin-Conjugating Enzyme E2 A, RAD6 Homolog A
Amino Acid Met1-Cys152
Construction Recombinant Human Ubiquitin-Conjugating Enzyme E2 A is produced by our E.coli expression system and the target gene encoding Met1-Cys152 is expressed with a GST, 6His tag at the N-terminus.
Protein Purity Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 45 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Ubiquitin-Conjugating Enzyme E2 (UBE2A) is a member of the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBE2A is required for postreplication repair of UV-damaged DNA. UBE2A Interacts with RAD18 and WAC.

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Keywords

UBE2A Protein, Human, Recombinant (GST, His) RAD6A HR6A Ubiquitin-Protein Ligase A UBE2A hHR6A Ubiquitin Carrier Protein A Ubiquitin-Conjugating Enzyme E2 A RAD6 Homolog A recombinant recombinant-proteins proteins protein

 

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