Rotavirus A (strain RVA/Cow/France/RF/1975/G6P6[1]) VP6 Protein (His)

Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.

Rotavirus A (strain RVA/Cow/France/RF/1975/G6P6[1]) VP6 Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.8 kDa and the accession number is P04509.

RV-A

E. coli

> 90% as determined by SDS-PAGE.

Intermediate capsid protein that self assembles to form an icosahedral capsid with a T=13 symmetry, which consists of 230 trimers of VP6, with channels at each of its five-fold vertices. This capsid constitutes the middle concentric layer of the viral mature particle. The innermost VP2 capsid and the intermediate VP6 capsid remain intact following cell entry to protect the dsRNA from degradation and to prevent unfavorable antiviral responses in the host cell during all the replication cycle of the virus. Nascent transcripts are transcribed within the structural confines of this double-layered particle (DLP) and are extruded through the channels at the five-fold axes. VP6 is required for the transcription activity of the DLP.