FBPase1 Protein, Human, Recombinant (His, E. coli)

Name: FBPase1 Protein, Human, Recombinant (His, E. coli)
Brand: TargetMol
SKU: TMPJ-00815
Rating: 4.5 (1 reviews)

(Synonyms: Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1) Copy Product Info

Synonyms: Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1

Catalog No. TMPJ-00815 Copy Product Info

Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

FBPase1 Protein, Human, Recombinant (His, E. coli)

Pack Size	Price	USA Stock	Global Stock
10 µg	$97	35 days	35 days
20 µg	$148	35 days	35 days
50 µg	$272	35 days	35 days
100 µg	$485	35 days	35 days
200 µg	$869	35 days	35 days
500 µg	$1,900	35 days	35 days
1 mg	$2,730	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Liquid

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
Species	Human
Expression System	E. coli
Tag	C-6xHis
Accession Number	P09467
Amino Acid	Ala2-Gln338
Construction	Ala2-Gln338
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 200 mM NaCl, 1 mM DTT, 1 mM EDTA, 20% Glycerol, pH 8.0.
Synonyms	Fructose-1, FBPase 1, FBP1, FBP, D-Fructose-1, 6-Bisphosphate 1-Phosphohydrolase 1, 6-Bisphosphatase 1
Research Background	Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.

Chemical Properties

Molecular Weight

38 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

FBP-1FBP 1

Related Tags: FBPase1 Protein, Human, Recombinant (His, E. coli) chemical structure | FBPase1 Protein, Human, Recombinant (His, E. coli) molecular weight