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TargetMol | Compound Library

Histone Modification Compound Library

Catalog No. L3500

A histone modification is a covalent post-translational enzymatic modification to histone proteins which includes methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation. Histone modification impacts gene expression by altering chromatin structure or recruiting histone modifiers. Therefore, histone modifications act in diverse biological processes such as transcriptional activation/inactivation, chromosome packaging, and DNA damage/repair. Thus, quantitative detection of various histone modifications would provide useful information for a better understanding of epigenetic regulation of cellular processes and the development of histone modifying enzyme-targeted drugs.

The TargetMol's Histone Modification Compound Library, a unique collection of 700 histone modification related compounds, can be used for research in histone modification and related drug screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L3500

Histone Modification Compound Library

sizeIn stock

  • 1 mg
  • 10 μL x 10 mM (in DMSO)
  • 20 μL x 10 mM (in DMSO)
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 700 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Epigenetic Reader Domain
Histone Methyltransferase
HDAC
Apoptosis
Sirtuin
Histone Demethylase
Histone Acetyltransferase
Autophagy
PROTACs
Endogenous Metabolite
HIV Protease
NF-κB
Akt
Antibacterial
MDM-2/p53
DNA/RNA Synthesis
PI3K
Parasite
JAK
GABA Receptor
TNF
Virus Protease
Ligands for Target Protein for PROTAC
Mitophagy
CDK
COX
Monoamine Oxidase
Wnt/beta-catenin
Antifungal
ERK
STAT
Phosphatase
PDE
mTOR
ROS
HIF/HIF Prolyl-Hydroxylase
AMPK
Adenosine Receptor
PARP
Antiviral
Nrf2
PPAR
Gamma-secretase
Caspase
RAAS
Histamine Receptor
Interleukin
AChR
MAO
EGFR
Bcl-2 Family
Carboxypeptidase
PD-1/PD-L1
Dehydrogenase
PKC
Molecular Glues
DNA Methyltransferase
TLR
p53
Angiotensin-converting Enzyme (ACE)
MMP
Dopamine Receptor
Influenza Virus
p38 MAPK
PKA
Estrogen Receptor/ERR
SARS-CoV
Ferroptosis
c-Myc
Reverse Transcriptase
Sodium Channel
NOD
Antibiotic
Adrenergic Receptor
Cytochromes P450
CaMK
transporter
Beta Amyloid
5-HT Receptor
FLT
NOD-like Receptor (NLR)
Topoisomerase
OXPHOS
Tyrosinase
Antioxidant
HBV
Tyrosine Kinases
NR4A
HSV
Cholinesterase (ChE)
Mitochondrial Metabolism
Potassium Channel
UGT
Androgen Receptor
Calcium Channel
HSP
IκB/IKK
Phospholipase
GPCR
Mdm2
GTPase
Reactive Oxygen Species
cAMP
TRP/TRPV Channel
IDO
Phosphorylase
Telomerase
PSMA
MEK
BMI-1
S6 Kinase
NOS
MyD88
Norepinephrine
P-gp
Pyroptosis
Cannabinoid Receptor
NO Synthase
GDNF
IAP
ABC Transporter
Monoamine Transporter
CCR
glycosidase
Casein Kinase
HER
Amino Acids and Derivatives
Serine Protease
Cell Cycle Arrest
Immunology/Inflammation related
Glucagon Receptor
NMDAR
IL Receptor
Chk
PLK
MRP
Antifolate
Adenylate cyclase
Bcr-Abl
Fatty Acid Synthase
PAD
Indoleamine 2,3-Dioxygenase (IDO)
Survivin
Aminopeptidase
Methionine Adenosyltransferase (MAT)
DNA-PK
Integrin
JNK
Serotonin Transporter
Glucosidase
TGF-beta/Smad
FOXO

Keywords