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Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO)

(Synonyms: Protein N, Nucleoprotein, Nucleocapsid protein) Copy Product Info

Synonyms: Protein N, Nucleoprotein, Nucleocapsid protein

Catalog No. TMPH-02366 Copy Product Info
Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 79.0 kDa and the accession number is P14239.
Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO)
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Pack SizePriceUSA StockGlobal StockQuantity
5 µg$129-In Stock
10 µg$216-In Stock
20 µg$360-In Stock
50 µg$543-In Stock
100 µg$745-In Stock
200 µg$1,07020 days20 days
500 µg$1,73020 days20 days
1 mg$2,53020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:reater than 90% as determined by SDS-PAGE
Appearance:Lyophilized powder
Color:White
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 79.0 kDa and the accession number is P14239.
Species
JUNV
Expression System
E. coli
TagN-6xHis-SUMO
Accession NumberP14239
Amino AcidMAHSKEVPSFRWTQSLRRGLSQFTQTVKSDVLKDAKLIADSIDFNQVAQVQRALRKTKRGEEDLNKLRDLNKEVDRLMSMRSVQRNTVFKAGDLGRVERMELASGLGNLKTKFRRAETGSQGVYMGNLSQSQLAKRSEILRTLGFQQQGTGGNGVVRVWDVKDPSKLNNQFGSVPALTIACMTVQGGETMNSVIQALTSLGLLYTVKYPNLSDLDRLTQEHDCLQIVTKDESSINISGYNFSLSAAVKAGASILDDGNMLETIRVTPDNFSSLIKSTIQVKRREGMFIDEKPGNRNPYENLLYKLCLSGDGWPYIGSRSQIIGRSWDNTSIDLTRKPVAGPRQPEKNGQNLRLANLTEIQEAVIREAVGKLDPTNTLWLDIEGPATDPVEMALFQPAGSKYIHCFRKPHDEKGFKNGSRHSHGILMKDIEDAMPGVLSYVIGLLPPDMVVTTQGSDDIRKLFDLHGRRDLKLVDVRLTSEQARQFDQQVWEKFGHLCKHHNGVVVSKKKRDKDAPFKLASSEPHCALLDCIMFQSVLDGKLYEEELTPLLPPSLLFLPKAAYAL
Construction1-564 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsProtein N, Nucleoprotein, Nucleocapsid protein
Research Background
Encapsidates the genome, protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC). Serves as template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and thereby participates in the suppression of interferon induction.
Chemical Properties
Molecular Weight79.0 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO) chemical structure | Junin mammarenavirus (JUNV) Nucleoprotein/NP Protein (His & SUMO) molecular weight