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D-DOPA

Name: D-DOPA
Brand: TargetMol
SKU: T37605
Rating: 4.5 (1 reviews)

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Catalog No. T37605Cas No. 5796-17-8

D-DOPA is an enantiomer of the dopamine precursor L-DOPA . It can be converted to L-DOPAviasequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, in rat kidney homogenates.1It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner.2Intraventricular administration of D-DOPA (200 μg/animal) increases striatal dopamine levels in rats.3D-DOPA (20 mg/kg, i.p.) induces contralateral turns in a rat model of Parkinson's disease induced by 6-OHDA .4

D-DOPA

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Catalog No. T37605Cas No. 5796-17-8

Pack Size	Price	Availability
50 mg	$198	35 days
100 mg	$388	35 days
250 mg	$797	35 days
500 mg	$1,290	35 days

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	197.19
Formula	C₉H₁₁NO₄
Cas No.	5796-17-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

0.1 M HCl: 10 mg/mL (50.71 mM), Sonication is recommended.

Solution Preparation Table

0.1 M HCl

	1mg	5mg	10mg	50mg
1 mM	5.0713 mL	25.3563 mL	50.7125 mL	253.5626 mL
5 mM	1.0143 mL	5.0713 mL	10.1425 mL	50.7125 mL
10 mM	0.5071 mL	2.5356 mL	5.0713 mL	25.3563 mL
20 mM	0.2536 mL	1.2678 mL	2.5356 mL	12.6781 mL
50 mM	0.1014 mL	0.5071 mL	1.0143 mL	5.0713 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc