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Synonyms: DTDP2, DSPP, DSP, DPP, DMP3, DGI1, DFNA39, dentinogenesis imperfecta 1, Dentin sialoprotein, Dentin sialophosphoprotein precursor, Dentin sialophosphoprotein, dentin phosphoryn, Dentin phosphoprotein, Dentin phosphophoryn
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-DSPP Polyclonal Antibody is a Rabbit antibody targeting DSPP. Anti-DSPP Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | DTDP2, DSPP, DSP, DPP, DMP3, DGI1, DFNA39, dentinogenesis imperfecta 1, Dentin sialoprotein, Dentin sialophosphoprotein precursor, Dentin sialophosphoprotein, dentin phosphoryn, Dentin phosphoprotein, Dentin phosphophoryn |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Expressed in teeth. DPP is synthesized by odontoblast and transiently expressed by pre-ameloblasts. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes two principal proteins of the dentin extracellular matrix of the tooth. The preproprotein is secreted by odontoblasts and cleaved into dentin sialoprotein and dentin phosphoprotein. Dentin phosphoprotein is thought to be involved in the biomineralization process of dentin. Mutations in this gene have been associated with dentinogenesis imperfecta-1; in some individuals, dentinogenesis imperfecta occurs in combination with an autosomal dominant form of deafness. Allelic differences due to repeat polymorphisms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human Dentin sialoprotein |
| Antigen Species | Human |
| Gene Name | DSPP |
| Gene ID | |
| Protein Name | Dentin sialophosphoprotein |
| Uniprot ID | |
| Biology Area | Cell differentiation,Bone,Other ECM Proteins,Bone,Calcium Binding Proteins |
| Function | DSP may be an important factor in dentinogenesis. DPP may bind high amount of calcium and facilitate initial mineralization of dentin matrix collagen as well as regulate the size and shape of the crystals. |
| Molecular Weight | Theoretical: 47/129 kDa. Actual: 129 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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