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Anti-CD64 Antibody-APC (1I453)
🥰Excellent
Catalog No. TMAY-00524A
Anti-CD64 Antibody-APC (1I453) is a APC-conjugated Rabbit antibody targeting CD64. Anti-CD64 Antibody-APC (1I453) can be used in FCM.
Anti-CD64 Antibody-APC (1I453)
Anti-CD64 Antibody-APC (1I453)
🥰Excellent
Catalog No. TMAY-00524A
Anti-CD64 Antibody-APC (1I453) is a APC-conjugated Rabbit antibody targeting CD64. Anti-CD64 Antibody-APC (1I453) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD64 Antibody-APC (1I453) is a APC-conjugated Rabbit antibody targeting CD64. Anti-CD64 Antibody-APC (1I453) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 1I453 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human CD64 expression on human whole blood monocytes. Cells were stained with APC-conjugated anti-Human CD64. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | FCM |
| Recommended Dose | 2 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD64/Fc gamma RI (rh CD64/Fc gamma RI; TMPY-04261; NP_000557.1; Met1-Pro288) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | High affinity immunoglobulin gamma Fc receptor I, also known as FCGR1 and CD64, is an integral membraneglycoprotein and a member of the immunoglobulin superfamily. CD64 is a high affinity receptor for the Fc region of IgG gamma and functions in both innate and adaptive immune responses. Receptors that recognize the Fc portion of IgG function in the regulation of immune response and are divided into three classes designated CD64, CD32, and CD16. CD64 is structurally composed of asignal peptidethat allows its transport to the surface of a cell, threeextracellularimmunoglobulin domainsof the C2-type that it uses to bind antibody, a hydrophobictransmembrane domain, and a short cytoplasmic tail. CD64 isconstitutivelyfound on only macrophages and monocytes, but treatment of polymorphonuclear leukocyteswith cytokines likeIFNγandG-CSFcan induce CD64 expression on these cells. The inactivation of the mouse CD64 resulted in a wide range of defects in antibody Fc-dependent functions. Mouse CD64 is an early participant in Fc-dependent cell activation and in the development of immune responses. |
| Conjucates | APC |
| Others Formats | Unconjugated/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Human CD64/Fc gamma RI Protein (TMPY-04261) |
| Antigen Species | Human |
| Biology Area | Fc Receptors |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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